Nebulized Dexmedetomidine, Ketamine, or Midazolam in Children Undergoing Adenotonsillectomy

Comparison of Nebulized Dexmedetomidine, Ketamine, or Midazolam for Premedication in Children Undergoing Adenotonsillectomy

The aim of this study is to compare between nebulized dexmedetomidine, ketamine, or midazolam for premedication in children undergoing adenotonsillectomy.

The aim of this study is to compare between nebulized dexmedetomidine, ketamine, or midazolam for premedication in children undergoing adenotonsillectomy.

Primary outcome:

• A five-point sedation score on arrival in the operating room 30 min after drug administration.

Secondary outcomes:

• Parental separation anxiety scale.
• Medication and mask acceptance scales.
• Hemodynamic variables.
• Recovery time.
• Postoperative face, legs, activity, cry, and consolability (FLACC) scale.
• Emergence Agitation scale.
• Adverse effects.

Inclusion Criteria:

• Children aged between 3-7 years.
• Both sexes.
• American society of anesthesiologists (ASA) physical status (I-II).
• Children undergoing adenotonsillectomy.

Exclusion Criteria:

• Patients with known allergy to the study drugs.
• Significant organ dysfunction.
• Cardiac dysrhythmia.
• Congenital heart disease.
• Use of psychotropic medication, and mental retardation