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This is a single-center, observational study including a retrospective cohort and a prospective validation cohort. The study aims to identify independent risk factors for inflammatory ureteral polyps in patients with ureteral calculi and develop a preoperative predictive model. The retrospective part will analyze clinical and imaging data of patients treated at the First Hospital of Jilin University between 2018 and 2025. The prospective part is currently recruiting participants to validate the model. The primary outcome is the intraoperative diagnosis of inflammatory ureteral polyps.
This is a bicentric bidirectional cohort study; retrospective cohort (n=629) has been fully enrolled, prospective cohort is ongoing consecutive enrollment.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Retrospective Cohort | This retrospective cohort consecutively enrolled 629 patients with ureteral calculi receiving surgical management from Jan 1, 2018 to Dec 31, 2025 at the First Hospital of Jilin University. Complete preoperative clinical and radiological data were extracted to screen independent risk factors for inflammatory ureteral polyps and construct a predictive logistic model. | ||
| Prospective Validation Cohort | This prospective validation cohort plans to consecutively recruit 150 eligible ureteral calculi patients from Mar 1, 2026 to Feb 1, 2027 to externally validate the preoperative predictive model derived from retrospective cohort data. |
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| Measure | Description | Time Frame |
|---|---|---|
| Number of Participants with Intraoperatively Confirmed Inflammatory Ureteral Polyps | The primary outcome is the presence or absence of inflammatory ureteral polyps confirmed by intraoperative pathology or direct visualization during ureteroscopy. | At the time of ureteroscopic surgery |
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Inclusion Criteria:
Exclusion Criteria:
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The study population includes adult patients with ureteral calculi who underwent ureteroscopic treatment at the First Hospital of Jilin University. The retrospective cohort includes patients treated between 2018 and 2025, and the prospective cohort is recruiting new patients for validation.
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| The First Hospital of Jilin University | Recruiting | Changchun | Jilin | 130021 | China |
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| ID | Term |
|---|---|
| D014514 | Ureteral Calculi |
| ID | Term |
|---|---|
| D053039 | Ureterolithiasis |
| D014515 | Ureteral Diseases |
| D014570 | Urologic Diseases |
| D052776 | Female Urogenital Diseases |
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| D005261 |
| Female Urogenital Diseases and Pregnancy Complications |
| D000091642 | Urogenital Diseases |
| D052878 | Urolithiasis |
| D014545 | Urinary Calculi |
| D052801 | Male Urogenital Diseases |
| D002137 | Calculi |
| D020763 | Pathological Conditions, Anatomical |
| D013568 | Pathological Conditions, Signs and Symptoms |