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the study comparess between laser therapy and vac to decide which on is superior
the vac will be used for 4 weeks the laser will be used for 3 session per weak for four weaks
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| laser group | Active Comparator | In this group of the study, will receive pulsed High intensity laser therapy (GaAs laser) in addition to traditional wound management for 3 sessions per week for four weeks at 980 nm laser irradiation at 15 W at 20hz laser emission potently stimulates defens in production in keratinocytes via ROS-mediated pathways. While these in vitro parameters highlight mechanistic efficacy, clinical translation for chronic wounds requires: Non-contact scanning techniques |
|
| negative pressure wound therapy | Active Comparator | In this group of the study, will receive negative pressure wound therapy in addition to traditional wound management for four weeks. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Laser therapy | Device | Pulsed high intensity laser therapy is applied to wound bed |
| |
| Measure | Description | Time Frame |
|---|---|---|
| wound surface area | imitoMeasure Mobil application: The ImitoMeasure app is a noncontact digital planimetry application that measures wound surface area and offers an advantage over other methods. The introduction of smartphones with high-definition cameras. These devices are not only portable and inexpensive, but they also provide the convenience of on-the-spot assessments. | one month |
| Measure | Description | Time Frame |
|---|---|---|
| qulity of life | Wound quality of life questionnaire The Wound-QoL questionnaire has been tested in a previous study, indicating that it is a reliable and valid tool for assessing HRQoL in chronic wounds. It contains 17 items, each with a 5-point Likert scale (0 = not at all, 4 = very much). | one month and three months |
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Inclusion Criteria:
-
The subject selection will be according to the following criteria:
Exclusion Criteria:
The potential participants will be excluded if they meet one of the following criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| ELshiek Zayed spicilized hospital | Giza | Egypt |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 37758743 | Background | Tang Y, Liu L, Jie R, Tang Y, Zhao X, Xu M, Chen M. Negative pressure wound therapy promotes wound healing of diabetic foot ulcers by up-regulating PRDX2 in wound margin tissue. Sci Rep. 2023 Sep 27;13(1):16192. doi: 10.1038/s41598-023-42634-9. | |
| 20958856 | Background | Leclere FM, Puechguiral IR, Rotteleur G, Thomas P, Mordon SR. A prospective randomized study of 980 nm diode laser-assisted venous ulcer healing on 34 patients. Wound Repair Regen. 2010 Nov-Dec;18(6):580-5. doi: 10.1111/j.1524-475X.2010.00637.x. Epub 2010 Oct 19. |
| Label | URL |
|---|---|
| Related Info | View source |
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| ID | Term |
|---|---|
| D053685 | Laser Therapy |
| ID | Term |
|---|---|
| D013812 | Therapeutics |
| D055011 | Ablation Techniques |
| D013514 | Surgical Procedures, Operative |
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| Negative pressure therapy is applied to the negative pressure group |
| Device |
It will be applied to patients with chronic wound |
|
| Related Info | View source |