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This study aims to focus on patients undergoing gynecological laparoscopic surgery and further evaluate the role of amisulpride in preventing postoperative nausea and vomiting in these patients.
Gynecological laparoscopic surgery patients usually combine multiple high-risk factors such as being 'female,' undergoing 'laparoscopic procedures,' and having 'gynecological surgery,' making the prevention and treatment of PONV a key focus and challenge.Among patients undergoing gynecological laparoscopic surgery, there is still a lack of targeted clinical data support.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Amisulpride | Receiving amisulpride (5mg) as postoperative prophylactic antiemetic drugs |
| |
| Tropisetron | receiving tropisetron (2mg) as postoperative prophylactic antiemetic drugs |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Tropisetron | Drug | and receive tropisetron (2mg) as a postoperative prophylactic antiemetic |
|
| Measure | Description | Time Frame |
|---|---|---|
| Complete remission (CR) rate within 24 hours postoperatively | The proportion of patients who, within 24 hours after surgery, experience neither vomiting episodes (vomiting/retching) nor require rescue antiemetic medication | 1 day |
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Inclusion Criteria:
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Agree and sign the informed consent form
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| ID | Term |
|---|---|
| D020250 | Postoperative Nausea and Vomiting |
| ID | Term |
|---|---|
| D011183 | Postoperative Complications |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D009325 | Nausea |
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| ID | Term |
|---|---|
| D000077526 | Tropisetron |
| D000077582 | Amisulpride |
| ID | Term |
|---|---|
| D007211 | Indoles |
| D006574 | Heterocyclic Compounds, 2-Ring |
| D000072471 | Heterocyclic Compounds, Fused-Ring |
| D006571 | Heterocyclic Compounds |
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| D012817 | Signs and Symptoms, Digestive |
| D012816 | Signs and Symptoms |
| D014839 | Vomiting |
| D001549 | Benzamides |
| D000577 | Amides |
| D009930 | Organic Chemicals |
| D001565 | Benzoates |
| D000146 | Acids, Carbocyclic |
| D002264 | Carboxylic Acids |
| D001555 | Benzene Derivatives |
| D006841 | Hydrocarbons, Aromatic |
| D006844 | Hydrocarbons, Cyclic |
| D006838 | Hydrocarbons |