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The goal of this clinical trial aims to explore the diagnostic efficacy and grading of prostate cancer by a novel MRI sequences such as MAGiC,OGSE,CEST,IVIM,etc.The main question it aims to answer is:
Can the novel non-contrast multiparametric MRI imaging improve the accuracy of diagnosis and grading of prostate cancer? For patients with clinical suspicion of prostate cancer, both conventional and new sequences magnetic resonance scans are conducted, with surgical or biopsy pathological results serving as the gold standard.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| the categorie is GG1 according to the ISUP grading standard |
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| the categorie is GG2 according to the ISUP grading standard |
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| the categorie is GG3 according to the ISUP grading standard |
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| the categorie is GG4 according to the ISUP grading standard |
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| the categorie is GG5 according to the ISUP grading standard |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| observational study | Other | The researchers will conduct observations, collect data and conduct follow-ups on the participants, but will not actively alter their treatment or health conditions. |
| Measure | Description | Time Frame |
|---|---|---|
| Microstructure parameters related to the OGSE sequence | Within one week after the MRI scan | |
| CEST sequence-related numerical values | Within one week after the MRI scan | |
| MAGIC sequence-related numerical values | Within one week after the MRI scan | |
| IVIM sequence-related numerical values | Within one week after the MRI scan |
| Measure | Description | Time Frame |
|---|---|---|
| Regular sequence-related numerical values | Within one week after the MRI scan |
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Inclusion Criteria:
Exclusion Criteria:
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Patients with clinical suspicion of prostate cancer, those who have a serum tPSA level greater than 4.0 ng/ml during outpatient examination, and patients with clinical manifestations of frequent urination, urgent urination and incomplete urination.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Qian Zhang | Contact | +86 15137562688 | zhangqian0194@163.com |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| The First Affiliated Hospital of Soochow University | Recruiting | Suzhou | Jiangsu | China |
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| ID | Term |
|---|---|
| D011471 | Prostatic Neoplasms |
| D004194 | Disease |
| ID | Term |
|---|---|
| D005834 | Genital Neoplasms, Male |
| D014565 | Urogenital Neoplasms |
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
| D005832 | Genital Diseases, Male |
| D000091662 | Genital Diseases |
| D000091642 | Urogenital Diseases |
| D011469 | Prostatic Diseases |
| D052801 | Male Urogenital Diseases |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
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| ID | Term |
|---|---|
| D019370 | Observation |
| ID | Term |
|---|---|
| D008722 | Methods |
| D008919 | Investigative Techniques |
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