Optimal Dosage of Melatonin for Preoperative Sedation in FESS

Optimal Melatonin Dosage for Effective Sedation, Hemodynamic Stability and Pain Control in Functional Endoscopic Sinus Surgery (FESS)

To determine the optimal dosage of Melatonin for preoperative sedation in patients undergoing FESS.

Inclusion Criteria:

- ASA 1 ASA 2 patients scheduled for elective FESS under general anesthesia

Exclusion Criteria:

• hypersensitivity or contraindication to the drug
• Severe psychiatric disorders.
• Regular use of sedatives or analgesics.
• Pregnancy or breastfeeding
• Significant systemic diseases such as severe cardiovascular, hepatic, or renal dysfunction.