Effect of Probiotic Supplementation on Gingival Health in Orthodontic Patients

Assessment of the Impact of the Probiotic Limosilactobacillus Reuteri Prodentis (DSM 17938 and ATCC PTA 5289) on Clinical and Microbiological Parameters in Orthodontically Treated Patients With Concomitant Gingivitis

This study evaluated the effect of probiotic supplementation on gingival health in orthodontic patients. Participants undergoing fixed orthodontic treatment were randomly assigned to receive either a probiotic preparation containing Limosilactobacillus reuteri or no The primary objective was to assess changes in gingival inflammation using clinical periodontal indices(BOP). Secondary outcomes included plaque accumulation(PI) . The results of this study may help determine whether probiotic supplementation can support gingival health during orthodontic treatment

This was a randomized, controlled clinical trial conducted in orthodontic patients with gingivitis. Participants were allocated to probiotic or no groups and followed for the duration of the orthodontic treatment period. Clinical periodontal parameters were recorded at baseline and at follow-up visits according to the study protocol

Inclusion Criteria:

• Generally healthy patient
• Age 18-59 years
• Fixed-appliance orthodontic treatment
• Plaque-induced gingivitis (BOP > 10%, PD ≤ 4 mm)

Exclusion Criteria:

• Hypersensitivity to product components
• Smoking
• Use of any probiotics within the past 30 days
• Antibiotic or other antimicrobial therapy within the past month
• Use of antibacterial chlorhexidine rinses within the past 2 weeks
• Age < 18 or > 59 years.