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Retrospective Single-center Analysis of Patients Presenting With Acute Neurological Symptoms, Aiming to Characterize the Frequency, Clinical Features, Diagnostic Pathways, and Healthcare Utilization of Patients with Functional Neurological Diseases
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| collection of patient data | Other | collection of patient data |
| Measure | Description | Time Frame |
|---|---|---|
| Frequency of FND | The primary endpoint is the proportion of patients presenting with acute neurological symptoms who receive a diagnosis or likely differential diagnosis of Functional Neurological Disorder (FND) during their index hospital admission. | At hospital discharge (index admission), up to 30 days from presentation |
| Measure | Description | Time Frame |
|---|---|---|
| Secondary Outcomes | Diagnostic Process Measures (%): Referral patterns and evaluation of alternative or concurrent neurological diagnoses. | At hospital discharge (index admission), up to 30 days from presentation |
| Secondary Outcomes |
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Inclusion Criteria:
Exclusion Criteria:
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Patients presenting with acute symptoms
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Urs Fisch, MD PhD | Contact | +41 61 265 2525 | urs.fisch@usb.ch |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University Hospital Basel | Recruiting | Basel | 4031 | Switzerland |
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| ID | Term |
|---|---|
| D003291 | Conversion Disorder |
| ID | Term |
|---|---|
| D013001 | Somatoform Disorders |
| D001523 | Mental Disorders |
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Diagnostic Resource Utilization (%): Clinical examination findings, neuroimaging, neurophysiological testing, and laboratory investigations.
| At hospital discharge (index admission), up to 30 days from presentation |
| Secondary Outcomes | Healthcare Utilization and Outcomes (%): Discharge destination, readmission, outpatient follow-up, and in-hospital mortality. | At hospital discharge (index admission), up to 30 days from presentation |
| Secondary Outcomes | Quality of Care Associations (%) Demographic and clinical variables associated with diagnostic performance and healthcare utilization. | At hospital discharge (index admission), up to 30 days from presentation |
| Secondary Outcomes | Comparative Analyses: FND vs Non-FND (%): Differences in diagnostics, resource utilization, escalation of care, and short-term outcomes. | At hospital discharge (index admission), up to 30 days from presentation |
| Secondary Outcomes | Subtype Analyses (%): Differences across FND subtypes in presentation, diagnostics, management, and outcomes. | At hospital discharge (index admission), up to 30 days from presentation |
| Secondary Outcomes | Time to Definitive Diagnosis (days) | At hospital discharge (index admission), up to 30 days from presentation |
| Secondary Outcomes | Length of Hospital Stay (days) | At hospital discharge (index admission), up to 30 days from presentation |