Bacteriophage Therapy for Orthopedic Implant-Associated Infections

Prospective, Single-Center, Single-Arm, Pre-Post Self-Controlled Study Evaluating the Efficacy and Safety of Bacteriophage Therapy in Orthopedic Implant-Associated Infections

A Prospective, Single-Center, Single-Arm Clinical Study with a Pre-Post Self-Controlled Design Evaluating the Efficacy and Safety of Bacteriophage Therapy for Refractory Orthopedic Implant-Associated Infections

Inclusion Criteria:

• Known allergy or hypersensitivity to bacteriophages or any components of the bacteriophage preparation;
• Pregnant or breastfeeding women;
• Participation in another interventional clinical trial within the study period;
• Lack of feasible routes of administration other than intravenous injection;
• Patients deemed unsuitable for participation in this study by the investigator;
• Inability or unwillingness of the subject to comply with study procedures.

Exclusion Criteria:

• Withdrawal of informed consent by the participant at any time during the study;
• Occurrence of serious adverse events related to bacteriophage therapy that, in the investigator's judgment, necessitate discontinuation of treatment.