The goal of this clinical trial is to learn if our research spectacles will lower the difference in prescription (spectacles degree) between the eyes in children between 6 to 13 years old with anisometropic myopia. Anisometropic myopia is when the difference in myopia prescription between the two eyes are more than 1 diopter. The main question it aims to answer is:

• How the eye responds to the research spectacles over time by measuring:

  1. Change in axial length: the physical length of the eye from front to back.

  2. Change in cycloplegic spherical equivalent refraction: an accurate measurement of the eye's prescription taken while the focusing muscles are temporarily relaxed with eye drops.

     Participants will:

• Wear the study spectacles

• Visit Essilor R&D Centre and an eye clinic for follow-up sessions

Inclusion Criteria:

1. Voluntary
2. Informed consent of parent/guardian and assent of participant
3. Age equal to or greater than 6 years old and less than 13 years at the time of signing informed consent and assent
4. SER equal or less than -0.50 D and equal or greater than .5.00 D with astigmatism not more than 2.50 D
5. Difference in SER (anisometropia) between two eyes .1.00 D
6. Best corrected visual acuity (BCVA) better than or equal to +0.20 LogMAR in each eye
7. Agree to wear study spectacles for .12 hours/day and 7 days/week
8. Willingness and ability to participate in investigation for 12 months and attend scheduled visits punctually
9. Agree for no concurrent involvement in other myopia control treatment

Exclusion Criteria:

1. History or presence of an ocular disease affecting refractive status
2. History or presence of strabismus
3. Presence of amblyopia
4. Current or previous use of atropine and/or orthokeratology
5. Known allergy to cycloplegic agents
6. Contraindication to cycloplegic agents
7. Cognitive or psychological vulnerability