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| Name | Class |
|---|---|
| Basque Center on Cognition, Brain and Language (BCBL) | UNKNOWN |
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The goal of this observational study is to investigate early neural mechanisms underlying the processing of spoken language, specifically the phenomenon of cortical tracking, and to determine whether these mechanisms can serve as early predictors of later language development outcomes in infants, including both typical and atypical trajectories.
The main questions it aims to answer are:
Participants will:
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| General population |
| ||
| Infants at familiar risk for language and learning impairment |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Electrophysiological recording | Other | Investigation of early neural markers using electrophysiology at 8 months |
|
| Measure | Description | Time Frame |
|---|---|---|
| Communicative Development | Standardized score in the McArthur-Bates's CDI: Words and Gestures (Infant form) adapted by Caselli et al. (2007). Percentile scores are employed to assess gestures, receptive, and expressive vocabulary. Higher scores signify better performance. | Age 18 months |
| Measure | Description | Time Frame |
|---|---|---|
| Global Development | Global development assessed with Bayley Scales of Infant and Toddler Development. Scaled scores by age (Mean = 10, Standard Deviation = 3) are computed. Higher scores mean better performance. | Age 18 months |
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Inclusion Criteria:
Exclusion Criteria:
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Participants will be recruited from general population in Lombardia (Italy).
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| IRCCS Eugenio Medea Associazione La nostra famiglia | Recruiting | Bosisio Parini | Lecco | 23842 | Italy |
EEG recordings at age 8 months and behavioral assessment data will be shared with researchers at Basque Center on Cognition, Brain and Language (BCBL) for data analysis purposes. The BCBL team will be involved in the project for stimuli creation, data analysis, and data comparison.
IPD will be available from 18/03/2026 to the end of project (February 2028).
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| ID | Term |
|---|---|
| D007805 | Language Development Disorders |
| ID | Term |
|---|---|
| D007806 | Language Disorders |
| D003147 | Communication Disorders |
| D019954 | Neurobehavioral Manifestations |
| D009461 | Neurologic Manifestations |
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| ID | Term |
|---|---|
| D009483 | Neuropsychological Tests |
| ID | Term |
|---|---|
| D011581 | Psychological Tests |
| D004191 | Behavioral Disciplines and Activities |
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| Behavioral Assessment | Behavioral | Behavioral Assessment at 8 months with Bayley-III Scales of Infant and Toddler Development. |
|
| D009422 | Nervous System Diseases |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |