Video-EEG Semiological Patterns in PNES | NCT07526467

Studies
Video-EEG Semiological Patterns in PNES

NCT07526467

Sponsor

Tepecik Training and Research Hospital

Status

Completed

Last Update Posted

Apr 13, 2026Actual

Enrollment

50Actual

Phase

Not provided

Conditions

Pnes

Interventions

Not provided

Countries

Turkey (Türkiye)

Protocol Section

Identification Module Status Module Sponsor/Collaborators Module Oversight Module Description Module Conditions Module Design Module Arms/Interventions Module Outcomes Module Eligibility Module Contacts/Locations Module References Module IPD Sharing Statement Module

Results Section

Participant Flow Module Baseline Characteristics Module Outcome Measures Module Adverse Events Module More Info Module

Annotation Section

Annotation Module

Document Section

Large Document Module

Derived Section

Miscellaneous Info Module Condition Browse Module Intervention Browse Module

Protocol Section

Identification Module

NCT ID

Results Section

No data available

No data is available for this block.

Annotation Section

No data available

No data is available for this block.

Document Section

No data available

No data is available for this block.

Derived Section

Miscellaneous Info Module

Version Holder

Status Module

Record Verification Date

Apr 2026

Overall Recruitment Status or Expanded Access Status

Completed

Last Known Status

Not provided

Delayed Posting

Not provided

Why Stopped

Not provided

Expanded Access Info

Start Date

Sep 1, 2025Actual

Primary Completion Date

Dec 1, 2025Actual

Completion Date

Apr 1, 2026Actual

First Submitted Date

Apr 6, 2026

First Submission Date that Met QC Criteria

Apr 6, 2026

First Posted Date

Apr 13, 2026Actual

Results Waived

Not provided

Results First Submitted Date

Not provided

Results First Submitted that Met QC Criteria

Not provided

Results First Posted Date

Not provided

Certification/Extension (aka Delayed Results) First Submitted Date

Not provided

Certification/Extension First Submitted that Passed QC Review

Not provided

Certification/Extension First Posted Date

Not provided

Last Update Submitted Date

Apr 6, 2026

Last Update Posted Date

Apr 13, 2026Actual

Sponsor/Collaborators Module

Responsible Party, by Official Title

Irem Fatma Uludag, Distinct Semiological Clusters of Psychogenic Non-Epileptic Seizures Identified by Video-EEG Monitoring, Tepecik Training and Research HospitalPrincipal Investigator

Lead Sponsor

Tepecik Training and Research HospitalOTHER

Collaborators

Not provided

Oversight Module

Has Data Monitoring Committee (DMC)

Not provided

Is FDA Regulated Drug

Is FDA Regulated Device

Is Unapproved Device

Not provided

Pediatric Postmarket Surveillance of a Device Product

Not provided

Product Exported from US

Not provided

FDAAA801 Violation

Not provided

Description Module

Brief Summary

This retrospective observational study evaluates semiological and electroclinical characteristics of psychogenic nonepileptic seizures (PNES) in adult patients who underwent video-EEG monitoring. The study aims to identify distinct semiological patterns and classify PNES events based on observable ictal features recorded during video-EEG monitoring.

Detailed Description

Psychogenic nonepileptic seizures (PNES) are paroxysmal events that resemble epileptic seizures but are not associated with ictal epileptiform activity on electroencephalography (EEG). Video-EEG monitoring is the gold standard for diagnosis.

In this retrospective observational study, video-EEG recordings and clinical data of 52 adult patients diagnosed with PNES were reviewed. Semiological features observed during recorded events were systematically evaluated and coded as binary variables.

Hierarchical cluster analysis (Ward's method with squared Euclidean distance) was used to identify semiological patterns. The aim was to define clinically meaningful clusters of PNES events and to describe their demographic and clinical correlates.

Design Module

Study Type

Observational

Number of References to an Expanded Access Study

Not provided

Expanded Access Types

Not provided

Patient Registry

Target Follow-Up Duration

Not provided

Phases

Not provided

Interventional Study Design

Allocation

Not provided

Intervention Model

Biospecimen

No data available

No data is available for this block.

Enrollment

50Actual

Label	Type	Description	Intervention Names
patients		patients with pnes underwent video eeg monitoring

Outcomes Module

Primary Outcomes

Measure	Description	Time Frame
Semiological cluster classification of PNES events	Classification of PNES events into semiological clusters (pauci-kinetic, hyperkinetic, hyperventilation-eye closure) based on ictal features identified during video-EEG monitoring.	Baseline (retrospective video-EEG analysis)

Secondary Outcomes

Measure	Description	Time Frame
pnes events	Eye closure during PNES events Hyperventilation during PNES events Abrupt onset of PNES events Abrupt termination of PNES events Hyperkinetic motor activity Presence or absence of excessive motor activity (e.g., thrashing movements). Tremor during PNES events Dystonic posturing Axial extension Axial immobility Pelvic thrusting Presence or absence of pelvic thrusting.	baseline

Other Outcomes

Not provided

Eligibility Module

Eligibility Criteria

Inclusion Criteria:

Adults aged 18 years and older Diagnosis of psychogenic nonepileptic seizures (PNES) confirmed by video-EEG monitoring Availability of complete video-EEG recordings capturing at least one typical event Availability of sufficient clinical and demographic data in medical records for retrospective evaluation

Exclusion Criteria:

Patients younger than 18 years Incomplete or poor-quality video-EEG recordings Absence of recorded typical PNES events during video-EEG monitoring Insufficient clinical documentation for retrospective analysis

Accepts Healthy Volunteers

Sex

All

Sex/Gender Based

Not provided

Sex/Gender Description

Not provided

Minimum Age

18 Years

Maximum Age

Not provided

Standard Ages

AdultOlder Adult

Study Population

This study population consists of adult patients diagnosed with psychogenic nonepileptic seizures (PNES) who underwent long-term video-EEG monitoring in a tertiary epilepsy center. All included patients had at least one recorded PNES event and sufficient clinical data available for retrospective analysis. Patients were identified through medical records and video-EEG databases, and no interventions were performed as part of the study.

Sampling Method

Non-Probability Sample

Name	Affiliation	Role
irem fatma uludag	Tepecik EAH	Principal Investigator

IPD Sharing Statement Module

Plan to Share IPD

Description

Not provided

Types

Not provided

Time Frame

Not provided

Access Criteria

Not provided

URL

Not provided