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This study investigates the level and distribution of suicide risk and learned suicide ability of patients with mood disorders, investigates the related risk factors of suicide and suicide ability formation of patients with mood disorders from multiple dimensions (biological, psychological, social and clinical perspectives) and clarifies their importance, forms a list of suicide risk factors, and establishes a prediction model of learned suicide ability formation. Upon enrollment, participants will undergo comprehensive assessments including blood and urine sample collection and scale evaluation. The collection of scientific blood and urine is mainly used for the exploration of molecular mechanism of disease occurrence and development, the discovery and verification of biomarkers. Scale evaluation includes: Beck Scale for Suicide Ideation , Columbia Suicide Severity Rating Scale,, Hamilton Depression Rating Scale , Hamilton Anxiety Rating Scale, PHQ-9, GAD-7, Personal and Social Function Scale , Schihan Disability Scale , Emotional Adjustment Difficulty Scale , Acquired Capability for Suicide Scale, Interpersonal Needs Questionnaire , Ottawa Self-Injury Scale, Chinese version of Stress Perception Scale and Beck Hopelessness Scale . Follow-up was carried out for 3 months, including whether suicide/self-injury occurred, current status, and some baseline questionnaires (such as BSI-CV, GAD-7, PHQ-9, HAMD-17,HAMA, etc.).
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| patients with mood disorders |
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| Measure | Description | Time Frame |
|---|---|---|
| Columbia Suicide Severity Rating Scale | Columbia Suicide Severity Rating Scale (C-SSRS) is a tool for evaluating the risk of individual suicide. It includes a series of questions to evaluate the frequency, intensity, persistence and concreteness of individual suicide behavior in the past period of time. The purpose of C-SSRS scale is to distinguish between suicidal ideation and suicidal attempt and higher scores mean a worse outcome. Developed by researchers from Columbia University, the scale is widely used in clinical and research fields to help identify and manage suicide risks. | baseline, 3 months |
| Measure | Description | Time Frame |
|---|---|---|
| Beck Scale for Suicide Ideation | Beck Scale for Suicide Ideation (BSI-CV) assesses the individual's thoughts about life and death and the severity of suicidal thoughts through series of questions. There are 19 items in the scale, which are divided into two dimensions: suicidal ideation and suicidal tendency. Each question is asked for two time periods, that is, the last week and the most depressed, melancholy or suicidal time in the past (that is, the most serious time). The scale adopts a three-level scoring system, that is, 0~2 points, and the total score is between 0~38 points. The higher the score, the stronger the suicidal ideation and the higher the risk of suicide. |
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Inclusion Criteria:
Exclusion Criteria:
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This study will recruit 300 patients meeting the diagnostic criteria of ICD-11 mood disorder.The 300 subjects, aged16 to 60 years old, come from Tianjin Anding Hospital's inpatient/outpatient services and must consent to participate.
Exclusion Criteria are as follows:(1) unable to understand the contents of the questionnaire;(2) Serious organic diseases such as cardiovascular disease, brain disease, liver disease and kidney disease, and weak body, which affect the respondents of the questionnaire;(3) Other circumstances that make it impossible or unwilling to cooperate with the completion of the questionnaire.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Xue Tian | Contact | +86-13602182093 | 576491743@qq.com |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Tianjin Anding Hospital | Recruiting | Tianjin | Tianjin Municipality | 300000 | China |
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| ID | Term |
|---|---|
| D019964 | Mood Disorders |
| D013405 | Suicide |
| ID | Term |
|---|---|
| D001523 | Mental Disorders |
| D016728 | Self-Injurious Behavior |
| D001526 | Behavioral Symptoms |
| D001519 | Behavior |
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| baseline, 3 months |
| Hamilton Depression Rating Scale | Hamilton Depression Rating Scale (HAMD-17), also known as Hamilton Depression Rating Scale, is a clinical tool for evaluating the severity of depressive symptoms, mainly evaluating patients' depressive symptoms in the past week, including mood, sleep, cognitive function, behavior and physical symptoms. According to the specific performance of patients, doctors or clinical evaluators will give corresponding scores. The total score ranges from 0 to 52 points. The higher the total score, the more serious the depressive symptoms are. | baseline, 3 months |
| Hamilton Anxiety Rating Scale | Hamilton Anxiety Rating Scale (HAMA) is a clinical tool for evaluating the severity of anxiety symptoms. The scale was compiled by psychologist Hamilton in 1959, and it is widely used in clinical diagnosis, treatment effect evaluation and research work in psychiatry. HAMA contains 14 items, covering psychological anxiety and physical anxiety. Each item is scored according to the severity of symptoms, and the higher the total score, the more serious the anxiety symptoms are. The total score ranges from 0 to 56 points. Scoring standards are usually divided into four grades: mild, moderate, severe and extremely severe. | baseline, 3 months |
| Patient Health Questionnare | Patient Health Question Nare (PHQ-9): It contains 9 questions, mainly focusing on depressed mood, lack of pleasure, sleep disorder, decreased energy, change of appetite, difficulty in concentration, reduced sense of self-worth, negative ideas or suicidal thoughts. Scores range from 0 to 27, with higher scores indicating more severe depressive symptoms. | baseline, 3 months |
| Generalized Anxiety Disorder | Generalized Anxiety Disorder-7 (GAD-7): Self-rating anxiety scale, a total of 7 items, respectively: 1 nervous anxiety, 2 uncontrollable worries, 3 excessive worries, 4 inability to relax, 5 akathisia, 6 irritability, 7 sense of foreboding. Scores range from 0 to 21, with higher scores indicating more severe anxiety symptoms. | baseline, 3 months |
| acquired capability for suicide scale | acquired capability for suicide scale (ACSS): The scale includes two sub-scales: reduced fear of death and improved physical pain tolerance, with a total of 20 topics. Each topic is scored on a 5-point Lickert scale of 1 (completely inconsistent) to 5 (completely consistent), of which 7 topics are reverse scoring. The higher the score, the lower the individual's fear of death and the higher the physical pain tolerance. | baseline, 3 months |
| Interpersonal Needs Questionnaire | The Interpersonal Needs Questionnaire (INQ) consists of two subscales: thwarted belongingness (9 items) and perceived burdensomeness (6 items). Each item is scored on a 7-point Likert scale ranging from 1 (not at all true for me) to 7 (very true for me), with 6 items reverse-scored. Scores range from 9 to 63 for thwarted belongingness and from 6 to 42 for perceived burdensomeness. Higher scores indicate greater levels of thwarted belongingness and perceived burdensomeness, reflecting more severe interpersonal distress and unmet interpersonal needs. | baseline, 3 months |
| Beck Hopelessness Scale | Beck Hopelessness Scale (BHS): Used to measure the degree of hopelessness that individuals feel. Hopelessness refers to the psychological state in which individuals are pessimistic about the future and believe that their efforts will not bring positive results. This feeling may be associated with depression, anxiety, and other mental health problems. The scale consists of 20 items, with scores ranging from 0 to 20, where higher scores indicate greater levels of hopelessness. | baseline, 3 months |