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This randomized controlled trial aims to compare the postoperative analgesic efficacy of M-TAPA block and OSTAP block in patients undergoing laparoscopic inguinal hernia repair. Pain scores, analgesic consumption, and patient satisfaction will be evaluated.
Prospective, randomized, single-blind, controlled study including 90 patients undergoing elective laparoscopic inguinal hernia repair. Patients will be randomized into three groups: M-TAPA, OSTAP, and control. Postoperative pain scores (VAS), analgesic consumption, time to first analgesic requirement, and patient satisfaction will be assessed over 24 hours.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| M-TAPA | Experimental | Bilateral M-TAPA block applied after surgery |
|
| OSTAP | Experimental | Bilateral OSTAP block applied after surgery |
|
| CONTROL | Other | No block applied and standart analgesia procedure |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Modified Thoracoabdominal Nerve Block Through Perichondrial Approach (M-TAPA) | Procedure | Ultrasound-guided bilateral M-TAPA block performed with 20 mL of 0.25% bupivacaine per side |
| Measure | Description | Time Frame |
|---|---|---|
| Total analgesic consumption in 24 hours | Total amount of dexketoprofen consumed in the first 24 hours after surgery | 24 hours postoperative |
| Measure | Description | Time Frame |
|---|---|---|
| Postoperative Pain Intensity (VAS Score) | Postoperative pain intensity assessed using the Visual Analog Scale (VAS, 0-10), where 0 indicates no pain and 10 indicates worst imaginable pain. | 0 (15 minutes), 2, 4, 8, 12, 16, and 24 hours postoperative |
| Time to First Analgesic Requirement |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Tahsin Simsek, MD | Kartal Dr. Lütfi Kirdar City Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Kartal Dr. Lütfi Kırdar City Hospital | Istanbul | Turkey (Türkiye) |
Individual participant data (IPD) will not be shared due to patient confidentiality, ethical considerations, and institutional regulations.
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| Oblique Subcostal Transversus Abdominis Plane Block (OSTAP) | Procedure | Ultrasound-guided bilateral OSTAP block performed with 20 mL of 0.25% bupivacaine per side |
|
| Standard Analgesia use (paracetamol, contramal) | Other | Patients received standard postoperative analgesia without regional block |
|
Time from the end of surgery to the first request for analgesic medication |
| Within 24 hours postoperative |
| Tramadol Consumption | Total amount of tramadol administered within the first 24 hours after surgery. | 24 hours postoperative |
| Patient Satisfaction Score | Patient satisfaction assessed using a Likert scale evaluating overall satisfaction with postoperative pain management | 24 hours postoperative |
| Incidence of Postoperative Nausea and Vomiting | Incidence of nausea and vomiting observed during the first 24 hours after surgery. | 24 hours postoperative |
| ID | Term |
|---|---|
| D010149 | Pain, Postoperative |
| ID | Term |
|---|---|
| D011183 | Postoperative Complications |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D010146 | Pain |
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |
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| ID | Term |
|---|---|
| D000082 | Acetaminophen |
| D014147 | Tramadol |
| ID | Term |
|---|---|
| D000083 | Acetanilides |
| D000813 | Anilides |
| D000577 | Amides |
| D009930 | Organic Chemicals |
| D000814 | Aniline Compounds |
| D000588 | Amines |
| D003511 | Cyclohexanols |
| D000441 | Hexanols |
| D005233 | Fatty Alcohols |
| D000438 | Alcohols |
| D004123 | Dimethylamines |
| D008744 | Methylamines |
| D008055 | Lipids |
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