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The goal of this observational study is to analyze the predictive value of early recurrence within different time windows for late recurrence, ultimately providing evidence-based support for defining the blanking period after pulsed field ablation and stratifying recurrence risk, with the goal of transforming clinical management strategies following pulsed field ablation. The main questions it aims to answer are:
Participants will undergo pulsed field ablation for the treatment of atrial fibrillation and will receive structured follow-ups at 1, 3, 6, and 12 months post-ablation. At each follow-up, a 24-hour Holter monitor will be performed to systematically assess the recurrence of atrial arrhythmias and the atrial arrhythmia burden.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Pulsed field ablation group |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| pulsed field ablation | Procedure | The patient underwent the ablation procedure using the pentaspline pulsed field ablation system. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Atrial arrhythmias | Including atrial fibrillation, atrial flutter, and atrial tachycardia, recorded as ≥10 seconds on a 12-lead electrocardiogram or ≥30 seconds on ambulatory electrocardiography (including single-lead patch devices). | from 3 months to 12 months post-ablation |
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Inclusion Criteria:
Exclusion Criteria:
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Consecutively selected patients with atrial fibrillation who underwent pulsed field ablation (PFA) in the Department of Cardiology at West China Hospital of Sichuan University from June 2025 to June 2026. Patients were screened strictly in accordance with the inclusion and exclusion criteria to enroll eligible participants as study subjects.
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| West China Hospital, Sichuan University | Recruiting | Chengdu | Sichuan | 610041 | China |
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| ID | Term |
|---|---|
| D001281 | Atrial Fibrillation |
| ID | Term |
|---|---|
| D001145 | Arrhythmias, Cardiac |
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
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