Exercise-induced Steroid Changes in Active Surveillance for Prostate Cancer

Exercise-induced Steroid Changes in Active Surveillance for Prostate Cancer

The purpose of this research study is to understand how a short session of a home-based bodyweight high-intensity interval training (HIIT) affects steroid hormone levels in men on active surveillance for low-grade prostate cancer.

Inclusion Criteria:

• Males 18 to 80 years old
• Diagnosis of localized prostate cancer
• Currently under active surveillance
• Ability to perform moderate-to-high intensity physical activity as demonstrated by self-assessment using the Physical Activity Readiness Questionnaire (PAR-Q+)
• Able to independently perform activities of daily living, without limitations in mobility
• Ability to read, write, speak, and understand English
• Able and willing to sign consent and comply with study requirements

Exclusion Criteria:

• Males currently receiving treatment for prostate cancer
• Diagnosis of metastatic prostate cancer
• Individuals with medical conditions contraindicating exercise
• Uncontrolled cardiovascular or circulatory diseases, hypertension, and diabetes, as determined by the study doctor or treating physician
• Ongoing use of medications affecting steroid metabolism
• Unable to sign consent and/or comply with study requirements