This quasi-experimental study aimed to evaluate the effects of sunflower oil and olive oil on the development of diaper dermatitis in hospitalized infants receiving antibiotic therapy. Infants aged 0-24 months were assigned to sunflower oil, olive oil, and control groups. Oils were applied to the diaper area after each diaper change. Infants were followed daily for 3-7 days, and diaper dermatitis severity was assessed using a four-stage clinical classification. The incidence of diaper dermatitis was compared between groups.

Diaper dermatitis is a common skin condition in infants and occurs more frequently in hospitalized infants receiving systemic antibiotics. This quasi-experimental study evaluated the preventive effects of sunflower oil and olive oil on diaper dermatitis. The study included 150 infants aged 0-24 months hospitalized and receiving antibiotic therapy. Participants were assigned to three groups: sunflower oil, olive oil, and control. In the intervention groups, oils were applied to the diaper area after each diaper change, while the control group received routine care. Infants were followed daily for 3-7 days, and diaper dermatitis severity was assessed using a four-stage clinical classification. The primary outcome was the incidence of diaper dermatitis. The study aimed to determine whether sunflower oil and olive oil reduce diaper dermatitis in hospitalized infants.

Inclusion Criteria:

• Infants aged 0-24 months
• Hospitalized and receiving systemic antibiotic therapy
• Expected hospital stay of 3-7 days
• Using disposable diapers
• Written informed parental consen

Exclusion Criteria:

• Premature or low birth weight infants
• Existing diaper dermatitis
• Diarrhea or oral candidiasis
• Chronic skin diseases (eczema, atopy, seborrheic dermatitis)
• Receiving antifungal treatment
• Neurological or urological anomalies
• Use of urinary catheter or bag
• Toilet-trained infants

Individual participant data will not be publicly shared due to privacy and ethical restrictions involving infant participants. De-identified data may be available from the corresponding author upon reasonable request.