The study compares the perceived treatment burden in patients undergoing intravitreal anti-VEGF treatment for either wet age related macular degeneration, macular edema after retinal vein occlusions or diabetic macular edema. This study is the first to the investigator's knowledge to compare treatment burden between all three patient groups, which also differ in age and socioeconomic circumstances. The results are of interest to all ophthalmologists who prescribe anti-VEGF treatments, as they show factors which can influence patient adherence und thus the efficacy of said therapies.

Inclusion Criteria:

• undergone a minimum of 5 IVT's and had visited the retina clinic for at least 6 months

Exclusion Criteria:

• eye surgery in the preceding six months
• notable cognitive impairment, such as dementia
• age <18 years

393 patients (305 with nAMD, 55 with CME and 33 with DME)