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biological assesment during intrusion of lower incisors
Assessment of the biological response of the corticision during intrusion of lower incisors A prospective clinical study
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| controlled | No Intervention | without corticision | |
| active group | Active Comparator | corticision group |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Corticision | Other |
|
| Measure | Description | Time Frame |
|---|---|---|
| Gingival crevicular fluid (GCF) prostaglandin E2 (PGE2) levels measured by enzyme-linked immunosorbent assay (ELISA) (pg/mL) | GCF samples will be collected from lower incisors using microcapillary tubes at baseline and during follow-up visits. Prostaglandin E2 levels will be quantified using ELISA kits and expressed in pg/mL to assess the biological response to corticision-assisted intrusion. | 12 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Amount of lower incisor intrusion measured in millimeters (mm) using cone beam computed tomography (CBCT) | CBCT imaging will be used to measure the vertical displacement of lower incisors in millimeters by comparing pre- and post-treatment positions. | 12 weeks |
| External apical root resorption measured in millimeters (mm) using cone beam computed tomography (CBCT) |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| alaa eldin elshahat shafay, post gradute student | Contact | +201016886788 | alaaelshafay9@gmail.com | |
| Mahmoud Fathy Aboelmahasen, lecturer | Contact | 01222993381 | MahmoudFathy.209@azhar.edu.eg |
| Name | Affiliation | Role |
|---|---|---|
| Ramadan Yu Abu-shahba, professor | Al-Azhar University, Faculty of Dental Medicine | Study Director |
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CBCT imaging will be used to assess external apical root resorption by comparing root lengths before and after treatment. |
| Time Frame: 12 weeks |