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Subarachnoid hemorrhage (SAH) represents a significant proportion of hemorrhagic strokes. Severe SAH in elderly patients is associated with poorer outcomes compared to younger cohorts. Better characterization of both short- and long -term prognosis in these patients is necessary to facilitate medical decision-making in the intensive care unit (ICU)
Primary Objective:
The primary objective is to identify prognostic factors associated with poor functional outcome or death at 6 months (± 2 months) in elderly patients admitted to the ICU for SAH.
Secondary Objectives:
To evaluate in-hospital mortality among elderly patients admitted to the ICU for SAH.
To describe the causes of in-hospital death (brain death, withholding/withdrawal of life-sustaining treatment [WOLST], other medico-surgical causes) in elderly patients admitted to the ICU for SAH.
To describe the care trajectory following hospital discharge for elderly patients admitted to the ICU for SAH.
To evaluate the mean length of stay in the ICU and in the hospital (acute care) for elderly patients admitted to the ICU for SAH.
To identify prognostic factors associated with poor functional outcome or death at 1 year in elderly patients admitted to the ICU for SAH.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Elderly aneurysmal SAH patients hospitalized in ICU | Patients hospitalized in ICU for aneurysmal subarachnoid hemorrhage between Juin 30, 2021 and Juin 30, 2025. Aged 70 years or over the day of admission in ICU. In accordance with French regulations , the study included patients who did not object to the use of their clinical data after receiving written information. |
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| Measure | Description | Time Frame |
|---|---|---|
| Modified Rankin Scale (MRS) et 6 months | MRS : scale from 1(no symptoms) to 6 (dead) Good outcome : 0 - 2 Bad outcome: 3 - 6 The MRS grade is either collected if already available in the medical file or estimated retrospectively based on the patient neurological evaluation. | 6 months after ICU discharge |
| Measure | Description | Time Frame |
|---|---|---|
| Intrahospital mortality | Intrahospital mortality = percentage of deaths occuring during the initial hospitalisation (in the ICU and the neurosurgical/neurological ward) | Day 28 |
| Cause of intrahospital death |
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Inclusion Criteria:
Exclusion Criteria:
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Adult patients admitted in ICU for aneurysmal subarachnoid hemorrhage in 4 University Hospital Centers in France (CHU Nancy, CHU Reims, HC de Lyon, CHU Lille) between Juin 30, 2021 et Juin 30, 2025
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Ionel M ALB, MD Intensive Care/Anesthesia | Contact | 0033-661028367 | im.alb@chru-nancy.fr |
| Name | Affiliation | Role |
|---|---|---|
| Viviane MARTIN, Chief of Research Departement | CHRU NANCY, DRCI | Study Chair |
| Elodie JEANBERT, Methodologist, Statistician | CHRU NANCY, DRCI | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Chru Nancy | Nancy | 54000 | France |
|
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| ID | Term |
|---|---|
| D013345 | Subarachnoid Hemorrhage |
| ID | Term |
|---|---|
| D020300 | Intracranial Hemorrhages |
| D002561 | Cerebrovascular Disorders |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
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Percentage of the following categories: cerebral death, WOLST, surgical causes and medical causes
| Day 28 |
| Destination upon hospital discharge | Percentage of the following categories: Discharge to Home versus Rehabilitation Unit versus Another Inpatient Ward (non-neurosurgical) | Day 28 |
| Modified Rankin Scale upon discharge from hospital. | MRS retrieved or estimated from patient's file data at the moment of ICU or neurosurgical ward discharge. | Day 28 |
| D009422 | Nervous System Diseases |
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
| D006470 | Hemorrhage |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |