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| Name | Class |
|---|---|
| Assiut University | OTHER |
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Inclusion criteria:
Patients diagnosed with ankylosing spondylitis according to Modified New York classification criteria 1984 (10).
Patients diagnosed with psoriatic arthritis (PsA patients (age ≥18 years) who fulfilled the CASPAR classification criteria for PsA 2010) (11).
b. Exclusion criteria: Patients with erythrodermic or pustular psoriasis, pregnant and lactating females, patients with autoimmune diseases e.g. systemic lupus erythematosus, or major systemic diseases, and patients receiving any immunosuppressive drug will be excluded from the study.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| ankylosing spondylitis | Experimental |
| |
| psoriatic arthritis patients | Experimental |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Detection of TNFAIP3 gene expression by real time PCR. | Diagnostic Test | Detection of TNFAIP3 gene expression by real time PCR. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Detection of TNFAIP3 gene expression. Ankylosing spondylitis (AS) is a chronic inflammatory condition primarily affecting the axial bone and sacroiliac joints. Its etiology involves genetic, environmental variables and demographic factors . | 18 months |
| Measure | Description | Time Frame |
|---|---|---|
| Detect relation between TNFAIP3 and ankylosing spondylitis apsoriatic arthritis activity. detection of TNFAIP3 gene expression by real time PCR will be done for every subject. | 20 months |
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Inclusion Criteria:
- 1. Patients diagnosed with ankylosing spondylitis according to Modified New York classification criteria 1984.
2. Patients diagnosed with psoriatic arthritis (PsA patients (age ≥18 years) who fulfilled the CASPAR classification criteria for PsA 2010)
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| asmaa mohmed, master | Contact | 01024850070 | a94asmaa@gmail.com |
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| ID | Term |
|---|---|
| D013167 | Spondylitis, Ankylosing |
| ID | Term |
|---|---|
| D000089183 | Axial Spondyloarthritis |
| D025242 | Spondylarthropathies |
| D025241 | Spondylarthritis |
| D013166 | Spondylitis |
| D013122 | Spinal Diseases |
| D001847 | Bone Diseases |
| D009140 | Musculoskeletal Diseases |
| D000844 | Ankylosis |
| D007592 | Joint Diseases |
| D001168 | Arthritis |
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