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This study aim to evaluate the agreement of ocular biometric parameters and intraocular lens between two devices (OA-2000 and Pentacam AXL) in patients with cataract.
Participants will be measured ocular biometric parameters once with each device in a random order by the same experienced operator.
This study was conducted as a prospective cross-sectional study to evaluate Agreement of ocular biometry and intraocular lens power between swept-source optical coherence tomography with Placido-disc topography (OA-2000) and Scheimpflug tomography with partial coherence interferometry (Pentacam AXL) in cataract patients The study performed at the Ophthalmology Outpatient Department, Burapha University Hospital, Chonburi, Thailand. The study protocol adhered to the tenets of the Declaration of Helsinki and received formal approval from the Institutional Review Board, Burapha University. Prior to the commencement of any measurements, all participants acknowledged comprehensive study information and provided written informed consent.
A total of 94 participants, aged 18 years or older, diagnosed with cataracts and scheduled for cataract surgery, were enrolled. Exclusion criteria included history of corneal trauma, prior ocular surgery, the use of contact lenses within two weeks of measurement, and the presence of other concurrent ocular pathologies. For each participant, right eye was preferentially selected for analysis; left eye was only utilized if right eye met any of the predefined exclusion criteria.
Measurement protocol Both devices, OA-2000 and Pentacam AXL Wave were calibrated daily before clinical use to ensure technical accuracy. All measurements were performed by one experienced examiner to eliminate inter-observer variability. Participants were instructed on proper head positioning and fixation, with a complete blink prior to each automated image capture. Measurements were obtained once for each device, with the sequence of instrumentation determined in a random order. The study evaluated several ocular biometric parameters: flat keratometry (K1), steep keratometry (K2), mean keratometry (Km), corneal astigmatism, vector analysis (J0 and J45), ACD, WTW, and AL. For the calculation of IOL power, The Acrysof SN60WF model (Alcon Laboratories, Fort Worth, Texas, USA) was used as the reference, utilizing the keratometric index of 1.3375. IOL power calculations were performed using three distinct formulas: SRK/T, Barrett Universal II, and Hoffer Q.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Cataract patients | Patients with cataract who were scheduled for cataract surgery |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Swept-source optical coherence tomography with Placido-disc topography | Device | Measurement technology using swept-source optical coherence tomography with Placido-disc topography |
| Measure | Description | Time Frame |
|---|---|---|
| Agreement of Intraocual lens power between OA-2000 and Pentacam AXL in cataract patients | Intraocular lens power calculated using SRK/T, Barrett Universal II, and Hoffer Q formulas in diopters | Immediately after participating in the study |
| Measure | Description | Time Frame |
|---|---|---|
| Agreement of flat keratometery(K1) between OA-2000 and Pentacam AXL in cataract patients | flat keratometery(K1) in diopters | Immediately after participating in the study |
| Agreement of steep keratometry(K2) between OA-2000 and Pentacam AXL in cataract patient |
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Inclusion Criteria:
Exclusion Criteria:
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Participants diagnosed with cataracts and scheduled for cataract surgery at the Ophthalmology Outpatient Department, Burapha University Hospital, Chonburi, Thailand
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| Name | Affiliation | Role |
|---|---|---|
| Rosepon Asawaworarit, M.D., M.Sc. | Burapha University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Burapha University | Chon Buri | 20131 | Thailand |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 29486009 | Background | Hua Y, Qiu W, Xiao Q, Wu Q. Precision (repeatability and reproducibility) of ocular parameters obtained by the Tomey OA-2000 biometer compared to the IOLMaster in healthy eyes. PLoS One. 2018 Feb 27;13(2):e0193023. doi: 10.1371/journal.pone.0193023. eCollection 2018. | |
| 29061989 | Background | Wang W, Miao Y, Savini G, McAlinden C, Chen H, Hu Q, Wang Q, Huang J. Precision of a new ocular biometer in eyes with cataract using swept source optical coherence tomography combined with Placido-disk corneal topography. Sci Rep. 2017 Oct 23;7(1):13736. doi: 10.1038/s41598-017-13800-7. |
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IPD used in the results publication
IPD and supporting information will be available one year after publicaiton and for two years period.
Direct contact to corresponding author
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|
| Scheimpflug tomography with partial coherence interferometry | Device | Measurement technology using Scheimpflug tomography with partial coherence interferometry |
|
|
steep keratometry(K2) in diopters |
| Immediately after participating in the study |
| Agreement of mean keratometry(Km) between OA-2000 and Pentacam AXL in cataract patient | Mean keratometry(Km) in diopters | Immediately after participating in the study |
| Agreement of anterior chamber depth (ACD) between OA-2000 and Pentacam AXL in cataract patients | Anterior chamber depth (ACD) in millimeters | Immediately after participating in the study |
| Agreement of white-to-white distance (WTW) between OA-2000 and Pentacam AXL in cataract patients | White-to-white distance (WTW) in millimeters | Immediately after participating in the study |
| Agreement of axial lenght (AL) between OA-2000 and Pentacam AXL in cataract patients | Axial lenght (AL) in millimeters | Immediately after participating in the study |
| Agreement of corneal astigmatism between OA-2000 and Pentacam AXL in cataract patients | corneal astigmatism in diopters | Immediately after participating in the study |
| Agreement of J0 between OA-2000 and Pentacam AXL in cataract patients | J0 is vector analysis of corneal astigmatism; measures astigmatism at 90° and 180° | Immediately after participating in the study |
| Agreement of J45 between OA-2000 and Pentacam AXL in cataract patients | J45 is vector analysis of corneal astigmatism; measures astigmatism at 45° and 135° | Immediately after participating in the study |
| 35609043 | Background | Asawaworarit R, Satitpitakul V, Taweekitikul P, Pongpirul K. Agreement of total corneal power between 2 swept-source optical coherence tomography and Scheimpflug tomography in normal and keratoconic patients. PLoS One. 2022 May 24;17(5):e0268856. doi: 10.1371/journal.pone.0268856. eCollection 2022. |
| 29223229 | Background | Ruiz-Mesa R, Abengozar-Vela A, Ruiz-Santos M. Comparison of a new Scheimpflug imaging combined with partial coherence interferometry biometer and a low-coherence reflectometry biometer. J Cataract Refract Surg. 2017 Nov;43(11):1406-1412. doi: 10.1016/j.jcrs.2017.08.016. |
| 28590285 | Background | Guimaraes de Souza R, Montes de Oca I, Esquenazi I, Al-Mohtaseb Z, Weikert MP. Updates in Biometry. Int Ophthalmol Clin. 2017 Summer;57(3):115-124. doi: 10.1097/IIO.0000000000000175. No abstract available. |
| ID | Term |
|---|---|
| D002386 | Cataract |
| ID | Term |
|---|---|
| D007905 | Lens Diseases |
| D005128 | Eye Diseases |
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