Post-exposure Influenza Prophylaxis in a Hospital Setting

Post-Exposure Influenza Chemoprophylaxis With Oseltamivir for Five Days vs Ten Days in Acute-Care Hospital: a Non-Inferiority Randomized Open-Label Study

The purpose of this study is to compare the efficacy of 5-day versus 10-day oseltamivir prophylactic treatment in patients who had been exposed to influenza in a hospital setting.

Inclusion Criteria:

• 18 years or older
• exposure to influenza during hospitalization
• risk factors for influenza complications
• consent for participation obtained

Exclusion Criteria:

• younger than 18 years
• hematological malignancy
• hospitalized in intensive care unit
• refusal to participate