EUSOL vs. PDGF Dressing for Diabetic Foot Ulcers

Comparison of EUSOL Dressing Versus Platelet Derived Growth Factor Dressing in Wound Contraction of Grade II Wagner Diabetic Foot Ulcers: A Randomized Controlled Trial

Diabetic foot ulcers are a major cause of morbidity and amputation. This randomized controlled trial will compare the efficacy of a traditional antiseptic dressing (EUSOL) with a modern biologic dressing containing Platelet-Derived Growth Factor (PDGF) in promoting wound contraction. The study aims to determine if PDGF dressing leads to better healing outcomes in patients with Grade II Wagner diabetic foot ulcers.

Inclusion Criteria:

• Diagnosis of diabetes mellitus.
• Presence of a Grade II Wagner diabetic foot ulcer (penetrating to subcutaneous tissue, without involvement of tendon, bone, or joint).
• Ulcer size less than 6 x 6 cm at baseline.

Exclusion Criteria:

• Uncontrolled diabetes
• Malnourished (BMI less than 20)
• HB less than 10
• ABPI less than 0.9
• Immunosuppression therapy
• Patients with malignancy or uncontrolled cardiopulmonary, neurological, or psychiatric disease.
• Severe active infection