TP-3654 Food Effect Study

A Phase 1 Randomized Study in Healthy Adult Participants to Assess the Relative Bioavailability of and Effect of Food on TP-3654 Capsule Formulations

This clinical trial will determine the bioavailability and effect of food on TP-3654 in healthy adult participants.

Inclusion Criteria:

• Participant has a BMI ≥ 18.5 and ≤ 32 kg/m2 at screening.
• Participant is generally healthy, as determined by the Investigator based on medical history, physical examination, clinical laboratory test results, vital signs, and 12-lead ECG at screening.
• Participant agrees to avoid the use of concomitant medications (except hormonal contraception or medication provided by the site staff under the direction of the Investigator) from time of screening through the final follow-up visit.
• Participant agrees to abstain from alcohol, recreational drugs (including marijuana), and nicotine from time of screening through the final follow-up visit.
• Participant agrees to use acceptable method of contraception during the duration of the study and up to 6 months after last dose.
• Participant agrees to not donate eggs or sperm during the study and up to 6 months after last dose.

Exclusion Criteria:

• Pregnancy
• History of alcohol and recreational drug use including smoking and/or use of nicotine products.
• Clinically significant medical history
• Exposure to other investigational product