Impact of Sleep Restriction on Blood Pressure Reactivity | NCT07489417

Studies
Impact of Sleep Restriction on Blood Pressure Reactivity

NCT07489417

Sponsor

University of Missouri-Columbia

Status

Recruiting

Last Update Posted

Mar 24, 2026Actual

Enrollment

45Estimated

Phase

Not Applicable

Conditions

Sleep
Blood Pressure

Interventions

Sleep Restriction

Countries

United States

Protocol Section

Identification Module Status Module Sponsor/Collaborators Module Oversight Module Description Module Conditions Module Design Module Arms/Interventions Module Outcomes Module Eligibility Module Contacts/Locations Module References Module IPD Sharing Statement Module

Results Section

Participant Flow Module Baseline Characteristics Module Outcome Measures Module Adverse Events Module More Info Module

Annotation Section

Annotation Module

Document Section

Large Document Module

Derived Section

Miscellaneous Info Module Condition Browse Module Intervention Browse Module

Protocol Section

Identification Module

NCT ID

Results Section

No data available

No data is available for this block.

Annotation Section

No data available

No data is available for this block.

Document Section

No data available

No data is available for this block.

Derived Section

Miscellaneous Info Module

Version Holder

Status Module

Record Verification Date

Mar 2026

Overall Recruitment Status or Expanded Access Status

Recruiting

Last Known Status

Not provided

Delayed Posting

Not provided

Why Stopped

Not provided

Expanded Access Info

Start Date

Mar 4, 2026Actual

Primary Completion Date

Aug 2027Estimated

Completion Date

Aug 2027Estimated

First Submitted Date

Mar 15, 2026

First Submission Date that Met QC Criteria

Mar 17, 2026

First Posted Date

Mar 24, 2026Actual

Results Waived

Not provided

Results First Submitted Date

Not provided

Results First Submitted that Met QC Criteria

Not provided

Results First Posted Date

Not provided

Certification/Extension (aka Delayed Results) First Submitted Date

Not provided

Certification/Extension First Submitted that Passed QC Review

Not provided

Certification/Extension First Posted Date

Not provided

Last Update Submitted Date

Mar 17, 2026

Last Update Posted Date

Mar 24, 2026Actual

Sponsor/Collaborators Module

Responsible Party, by Official Title

Jacqueline K Limberg, PhD, Associate Professor, University of Missouri-ColumbiaPrincipal Investigator

Lead Sponsor

University of Missouri-ColumbiaOTHER

Collaborators

Not provided

Oversight Module

Has Data Monitoring Committee (DMC)

Is FDA Regulated Drug

Is FDA Regulated Device

Is Unapproved Device

Not provided

Pediatric Postmarket Surveillance of a Device Product

Not provided

Product Exported from US

Not provided

FDAAA801 Violation

Not provided

Design Module

Study Type

Interventional

Number of References to an Expanded Access Study

Not provided

Expanded Access Types

Not provided

Patient Registry

Not provided

Target Follow-Up Duration

Not provided

Phases

Not Applicable

Interventional Study Design

Allocation

Biospecimen

No data available

No data is available for this block.

Enrollment

45Estimated

Arms/Interventions Module

Arm Groups

Label	Type	Description	Intervention Names
Sleep Restriction	Experimental	You will be asked to shorten your sleep to four hours.	Behavioral: Sleep Restriction
Normal Sleep	No Intervention	You will be asked to sleep for 7-9 hours.

Interventions

Name	Type	Description	Arm Group Labels	Other Names
Sleep Restriction	Behavioral	You will be asked to shorten your sleep to four hours.	Sleep Restriction

Outcomes Module

Primary Outcomes

Measure	Description	Time Frame
Blood Pressure	Blood pressure	Baseline and during the last 1-minute of stress

Secondary Outcomes

Not provided

Other Outcomes

Not provided

Eligibility Module

Eligibility Criteria

Inclusion Criteria:

Healthy adult men and women
18-45 years of age
BMI < 25 kg/m² (normal weight group) or ≥ 30 kg/m² (obesity group)
Non-pregnant, non-breastfeeding, and non-nicotine users
Self-reported history of normal sleep duration (7-9 hours/night) and bedtime prior to midnight
Premenopausal

Exclusion Criteria:

No acute or chronic conditions
Taking no medications known to affect sleep, autonomic, metabolic, or cardiovascular function
Self-reported history of irregular sleep
Self-reported history of hepatic, renal, pulmonary, cardiovascular, or neurological disease, stroke or neurovascular disease, bleeding/clotting disorders, sleep apnea or other sleep disorders, diabetes, history of alcoholism or substance abuse, major cardiovascular event or surgical procedure within the past three months, or hypertension

Accepts Healthy Volunteers

Yes

Sex

All

Sex/Gender Based

Not provided

Sex/Gender Description

Not provided

Minimum Age

18 Years

Maximum Age

45 Years

Standard Ages

Adult

Study Population

Not provided

Sampling Method

Not provided

Contacts/Locations Module

Central Contacts

Name	Role	Phone	Extension	Email
Jacqueline Limberg	Contact	1-573-882-2544		limberglab@missouri.edu

Overall Officials

Not provided

Locations

Facility	Status	City	State	ZIP	Country	Contacts
University of Missouri	Recruiting	Columbia	Missouri	65211	United States

IPD Sharing Statement Module

Plan to Share IPD

Undecided

Description

Not provided

Types

Not provided

Time Frame

Not provided

Access Criteria

Not provided

URL

Not provided