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The goal of this observational study is to evaluate the diagnostic value and safety of capsule endoscopy in patients with gastrointestinal bleeding. The main questions it aims to answer are:
What is the overall detection rate of bleeding lesions using capsule endoscopy? What is the completion rate of capsule endoscopy, and how long does it take for the capsule to pass through the stomach and small intestine? What adverse events (such as capsule retention) occur during or after the procedure?
Participants who underwent capsule endoscopy for gastrointestinal bleeding at Changhai Hospital between January 2021 and December 2025 will:
Have their existing medical records (including endoscopy reports, procedure notes, and follow-up records) reviewed by researchers Have their personal information anonymized and protected Not be required to undergo any additional tests, procedures, or visits This is a retrospective study that only analyzes previously collected data. No new interventions or patient contact is involved.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Retrospective GI Bleeding Cohort | Patients aged ≥18 years who underwent capsule endoscopy for gastrointestinal bleeding at Changhain Hospital from January 2021 to December 2025. This study was a retrospective medical record analysis without any intervention measures. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| capsule endoscopy | Device | This study involves a retrospective analysis of existing data from patients who underwent small-bowel capsule endoscopy for gastrointestinal bleeding between 2021-2025. No new intervention is administered. |
| Measure | Description | Time Frame |
|---|---|---|
| The detection rate of capsule endoscopy for lesions causing gastrointestinal bleeding. | Definition: The proportion of cases among all those included in the analysis where capsule endoscopy identified at least one positive lesion | From enrollment to the end of treatment at 2 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Detection rate of other lesions | Calculate the lesion detection rates for the esophagus, stomach, small intestine (further divided into jejunum and ileum), and colorectum separately. The patients were divided into overt bleeding group and occult bleeding group, and the differences in lesion detection rates between the two groups were compared. | From enrollment to the end of treatment at 2 weeks |
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Inclusion Criteria:
Exclusion Criteria:
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Participants who underwent magnetically controlled capsule endoscopy for gastrointestinal bleeding at Changhai Hospital between January 2021 and December 2025
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Zhuan Liao | Contact | 130 6192 1980 | zhuanleo@126.com |
| Name | Affiliation | Role |
|---|---|---|
| Zhuan Liao | Department of Gastroenterology, Changhai Hospital | Principal Investigator |
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| ID | Term |
|---|---|
| D006471 | Gastrointestinal Hemorrhage |
| ID | Term |
|---|---|
| D005767 | Gastrointestinal Diseases |
| D004066 | Digestive System Diseases |
| D006470 | Hemorrhage |
| D010335 | Pathologic Processes |
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| ID | Term |
|---|---|
| D053704 | Capsule Endoscopy |
| ID | Term |
|---|---|
| D016099 | Endoscopy, Gastrointestinal |
| D016145 | Endoscopy, Digestive System |
| D004724 | Endoscopy |
| D003949 | Diagnostic Techniques, Surgical |
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| Completion Rate of Inspections: | Definition: The proportion of capsules that successfully pass through the stomach into the duodenum and complete the examination of the entire small intestine before the battery runs out. Gastric transit time and intestinal transit time: Definition: Record the time capsule stays in the stomach and the duration of its movement in the small intestine. | From enrollment to the end of treatment at 2 weeks |
| Safety Evaluation: | Adverse event incidence rate. | From enrollment to the end of treatment at 2 weeks |
| D013568 |
| Pathological Conditions, Signs and Symptoms |
| D019937 | Diagnostic Techniques and Procedures |
| D003933 | Diagnosis |