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Mixed astigmatism is a type of refractive error in which the two principal steep and flat meridians focus the light in front and behind the retina, respectively.1 Laser vision correction (LVC) for mixed astigmatism is challenging as it involves a bitoric ablative pattern to flatten the steepest meridian and steepen the flattest one. The aim of the current study was to compare the visual and refractive outcomes of FS-LASIK versus single-step TransPRK for treatment of patients with mixed astigmatism.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Femtosecond laser-assisted laser in situ keratomileusis (FS-LASIK) group |
| ||
| Single-step transepithelial photorefractive keratectomy (TransPRK) group |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Femtosecond laser-assisted LASIK | Procedure | Patients in the FS-LASIK group underwent flap creation using the femtosecond laser WaveLight FS200® (Alcon lab, TX, USA). After flap creation, wave-front optimized stromal ablation was performed with WaveLight EX-500 (WaveLight®; Alcon Laboratories, Fort Worth, TX, USA) for mixed astigmatism correction. |
| Measure | Description | Time Frame |
|---|---|---|
| Uncorrected distance visual acuity (UDVA) | Visual acuity measurement using Snellen's Acuity Chart converted to logMAR notation. | 24 months |
| Corrected distance visual acuity (CDVA) | Corrected visual acuity measurement using Snellen's Acuity Chart and converted to logMAR notation. | 24 months |
| Postoperative refraction | Manifest sphere and cylinder measured by Topcon Auto-Keratorefractometer | 24 months |
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Inclusion Criteria:
Exclusion Criteria:
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This was a retrospective comparative study conducted at Tiba eye center (private practice).
The study reviewed and analyzed the records of patients with mixed astigmatism who underwent femtosecond laser-assisted LASIK (FS-LASIK group) or single-step TransPRK (TransPRK group) and completed 24 months of follow-up.
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| TIBA Eye Center | Asyut | Asyut Governorate | 71515 | Egypt |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 33252566 | Background | Kaluzny BJ, Verma S, Piotrowiak-Slupska I, Kaszuba-Modrzejewska M, Rzeszewska-Zamiara J, Stachura J, Arba-Mosquera S. Three-year outcomes of mixed astigmatism correction with single-step transepithelial photorefractive keratectomy with a large ablation zone. J Cataract Refract Surg. 2021 Apr 1;47(4):450-458. doi: 10.1097/j.jcrs.0000000000000476. | |
| 35167040 |
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| ID | Term |
|---|---|
| D001251 | Astigmatism |
| ID | Term |
|---|---|
| D012030 | Refractive Errors |
| D005128 | Eye Diseases |
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|
| Single-step transepithelial PRK | Procedure | Patients in the single-step TransPRK group underwent StreamLight® PRK in WaveLight EX-500 Excimer laser (WaveLight®; Alcon Laboratories, Fort Worth, TX, USA). In a single step, epithelial ablation (based on epithelial mapping) followed by stromal ablation for mixed astigmatism correction, were accomplished. |
|
| Moshirfar M, Durnford K, Megerdichian A, Thomson A, Martheswaran T, West W Jr, McCabe S, Ronquillo Y, Hoopes P. Refractive Outcomes After LASIK for the Treatment of Mixed Astigmatism with the Allegretto WaveLight EX500. Ophthalmol Ther. 2022 Apr;11(2):785-795. doi: 10.1007/s40123-022-00472-4. Epub 2022 Feb 15. |