Glycaemic Index Measurement of an Oral Nutritional Supplement With Biomarker Assessment and Lifestyle Monitoring in Healthy Participants

Glycaemic Index Measurement of an Oral Nutritional Supplement With Biomarker Assessment and Lifestyle Monitoring in Healthy Participants

This clinical trial evaluates the postprandial glycaemic response to an Oral Nutritional Supplement (ONS), a Food for Special Medical Purposes (FSMP), in healthy adults. The study uses a crossover design comparing the ONS to the reference product glucose.

Each participant will consume both test and reference products on three separate occasions each, overall on six test days.

Inclusion Criteria:

• Aged ≥18 and ≤60 years, adult healthy Caucasian or Chinese participants
• Stable body weight within the Body Mass Index between 18.5 kg/m2 and 27.9 kg/m2 (inclusive)
• Glycated hemoglobin < 6%/< 42 mmol/mol

Exclusion Criteria:

• Pregnant or lactating,
• Body fat percentage exceeding 30%,
• Known history of metabolic diseases or diabetes mellitus,
• Major medical or surgical event requiring hospitalization within the preceding 3 months
• Medical condition(s) or medication(s) or herbal effects known to affect glucose regulation, tolerance or appetite and/or which influence digestion and absorption of nutrients (excluding oral contraceptives),
• Use of steroids, protease inhibitors, amphetamines or antipsychotics