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| Name | Class |
|---|---|
| Oxford Brookes University | OTHER |
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This clinical trial evaluates the postprandial glycaemic response to an Oral Nutritional Supplement (ONS), a Food for Special Medical Purposes (FSMP), in healthy adults. The study uses a crossover design comparing the ONS to the reference product glucose.
Each participant will consume both test and reference products on three separate occasions each, overall on six test days.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Group A (Treatment sequence: Glucose, ONS, Glucose, ONS, Glucose, ONS) | Other | Participants will receive the test product and the control product alternately. They will be randomly assigned to one of the two treatment sequence groups with 15 participants in each group. The randomization will be stratified by race/ethnicity (Chinese, Caucasian). |
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| Group B (Treatment sequence: ONS, Glucose, ONS, Glucose, ONS, Glucose) | Other | Participants will receive the test product and the control product alternately. They will be randomly assigned to one of the two treatment sequence groups with 15 participants in each group. The randomization will be stratified by race/ethnicity (Chinese, Caucasian). |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| ONS | Dietary Supplement | Each administration of the test product (ONS) will represent 25 g of glycaemic carbohydrates. |
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| Measure | Description | Time Frame |
|---|---|---|
| Glycaemic Index (GI) of ONS | Three GIs for each repeated test of the ONS (based on capillary blood glucose) and their average GI (mean value) will be calculated as per ISO 26642. | Blood samples will be obtained at -5, 0, 15, 30, 45, 60, 90, and 120 minutes. |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Sangeetha Thondre, Dr | Contact | +44 1865 534136 | pthondre@brookes.ac.uk |
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| ID | Term |
|---|---|
| D005947 | Glucose |
| ID | Term |
|---|---|
| D006601 | Hexoses |
| D009005 | Monosaccharides |
| D000073893 | Sugars |
| D002241 | Carbohydrates |
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| glucose | Other | The test product will be compared with the reference product glucose (glucose monohydrate dissolved in 250 ml water). Each administration of the reference product will represent 25 g of glycaemic carbohydrates. |
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