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| ID | Type | Description | Link |
|---|---|---|---|
| SHDC12025144 | Other Grant/Funding Number | Shanghai Hospital Development Center Foundation |
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This retrospective single-center observational study is designed to develop and internally validate a multi-output machine learning model for predicting 1-year postoperative refractive prediction error after small incision lenticule extraction (SMILE). The primary modeling target is 1-year spherical equivalent prediction error. Secondary targets include J0 prediction error, J45 prediction error, and postoperative uncorrected distance visual acuity in logarithm of the minimum angle of resolution. A secondary objective is to use the prediction framework to derive individualized nomogram recommendations and to compare these recommendations with ZEISS 4.0 planning in a virtual treatment-planning analysis.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Training Cohort | Eyes included in the prespecified training dataset for development of the multi-output machine learning model. | ||
| Test Cohort | Eyes included in the prespecified independent test dataset for internal validation of the multi-output machine learning model. |
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| Measure | Description | Time Frame |
|---|---|---|
| Mean Absolute Error of Predicted 1-Year Postoperative Spherical Equivalent Prediction Error | Model performance for prediction of 1-year postoperative spherical equivalent prediction error, assessed in diopters. | 1 year after SMILE |
| Measure | Description | Time Frame |
|---|---|---|
| Mean Absolute Error of Predicted 1-Year Postoperative J0 Prediction Error | Model performance for prediction of the cardinal astigmatic vector component (J0), assessed in diopters. | 1 year after SMILE |
| Mean Absolute Error of Predicted 1-Year Postoperative J45 Prediction Error |
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Inclusion Criteria:
Exclusion Criteria:
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People with moderate myopia who have undergone SMILE surgeries
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Shanghai Tenth People's Hospital | Shanghai | Shanghai Municipality | 200072 | China |
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| ID | Term |
|---|---|
| D009216 | Myopia |
| D001251 | Astigmatism |
| D012030 | Refractive Errors |
| ID | Term |
|---|---|
| D005128 | Eye Diseases |
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Mean Absolute Error of Predicted 1-Year Postoperative J45 Prediction Error |
| 1 year after SMILE |