Standardizing Swallow Pressure Measurements

Pharyngeal High Resolution Manometry Standardization of Metrics

This study aims to directly compare and contrast swallowing pressure and impedance measurements obtained from two high-resolution manometry (HRM) systems: the Laborie LMT Pharyngeal System and the Medtronic ManoScan ESO HRM System in healthy adult volunteers. The primary objective is to determine how differences in catheter diameter, sensor configuration, and acquisition platforms influence measurement outcomes. Twenty-five healthy adults will participate in a single, approximately 2-hour visit; the study will be open for one year for data collection and two years for data analysis.

The primary objective is to obtain, compare, and contrast directly the measured swallow between the Laborie Pharyngeal HRM impedance system with the 3.7 mm catheter and the Medtronic HRM impedance system with the 4.2 mm catheter in the same setting with normal healthy volunteers.

Inclusion Criteria:

• without known swallowing disorders

Exclusion Criteria:

• Known swallowing disorder
• Allergy to topical anesthetic
• Allergy to food relevant to study participation (e.g. lactose intolerance)
• Inability to follow direction or remain calm during the experiment.