This study evaluates the allergic (immunogenic) response following application of a collagen-based material in healthy adult volunteers using a standardized skin prick test. Skin responses will be assessed at multiple time points following application.

Inclusion Criteria:

• Healthy adult volunteers
• Age 18 to 70 years
• Able to comply with study procedures

Exclusion Criteria:

• Use of medications that may interfere with skin test responses
• Known allergy to personal care products or adhesives
• History of autoimmune disease
• History of cancer
• Uncontrolled chronic medical conditions
• History of dermatographism
• Known allergy to study materials
• Known hypersensitivity to study materials
• Active dermatitis or eczema at the test site

The plan for sharing individual participant data (IPD) has not yet been determined. Any potential sharing of de-identified participant-level data will be evaluated by the sponsor after study completion and in accordance with applicable privacy regulations and sponsor policies.