Multimodal Clinical Study of Electroconvulsive Therapy and Magnetic Seizure Therapy

Multimodal Clinical Study of Electroconvulsive Therapy and Magnetic Seizure Therapy

To compare the efficacy and tolerability of Electroconvulsive Therapy (ECT) and Magnetic Seizure Therapy (MST) in patients with major depressive disorder (MDD).

Inclusion Criteria:

• Aged 12-80 years;
• Diagnosis confirmed by two psychiatrists per DSM-5;
• Stable medication regimen pre-enrollment;
• Indicated for neuromodulation OR with visual field defects.

Exclusion Criteria:

• Major systemic diseases;
• Prior neuromodulation within 3 months;
• Pregnancy or potential pregnancy;
• Metal implants or claustrophobia.