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This is a retrospective-prospective study conducted at Zhongshan Hospital, Fudan University, to explore portal vein thrombosis (PVT) in patients with cirrhosis and gastroesophageal varices (GEV). It aimed to provide insights into the diagnosis, follow-up, and factors influencing PVT recanalization, to help patients, families, and healthcare providers understand the disease and related clinical management.
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| Measure | Description | Time Frame |
|---|---|---|
| PVT recanalization at 1 year | From the first abdominal imaging assessment after admission, until the occurrence of PVT recanalization at 1 year, death, or the last follow-up, whichever came first |
| Measure | Description | Time Frame |
|---|---|---|
| Occurrence of all-cause death (competing event) | From the date of admission confirmation of PVT to the occurrence of death, or the last follow-up, whichever came first | |
| PVT recanalization at 5 years | From the first abdominal imaging assessment after admission, until the occurrence of PVT recanalization at 5 year, death, or the last follow-up, whichever came first |
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Inclusion Criteria:
diagnosed as cirrhosis and confirmed gastroesophageal varices by endoscopy;
Exclusion Criteria:
patients with hepatocellular carcinoma;
patients with extrahepatic malignancies;
history of liver transplantation or TIPS;
lack of information regarding anticoagulation therapyï¼›
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This study enrolled adult patients with cirrhosis and confirmed gastroesophageal varices who presented to Zhongshan Hospital, Fudan University, and were diagnosed with portal vein thrombosis (PVT)upon admission.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Siyu Jiang, Dr. | Contact | +86-15121068078 | ksjsy1996926@126.com |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Recruiting | Shanghai | Shanghai Municipality | 200032 | China |
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| ID | Term |
|---|---|
| D005355 | Fibrosis |
| D006975 | Hypertension, Portal |
| ID | Term |
|---|---|
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D008107 | Liver Diseases |
| D004066 | Digestive System Diseases |
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| Occurrence of non-improved PVT | defined as unchanged thrombus size, <50% thrombus reduction, or thrombus extension to new venous segments | From the date of admission confirmation of PVT to the last radiological follow-up at 1 year, or death, whichever came first |