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Primary Objective: Compare 6-month graft success rates between 0.5 mm sliced and 1.8 mm full-thickness tragal cartilage grafts.(3) H1: Sliced cartilage yields ≥90% success versus ≤80% for full-thickness.(3) H0: No difference between arms.
Secondary Objectives:
chronic suppurative otitis media with tympanic membrane perforation impacts a large number of adults worldwide, more in rural Upper Egypt due to recurrent infections.(1) These perforations cause ongoing ear discharge, hearing impairment, quality-of-life decline, and increased healthcare costs.(1) Conventional temporalis fascia grafting achieves 80-90% success in small defects but drops below 70% for subtotal/large perforations (>50%tympanic membrane area) or with Eustachian tube issues.(2) Tragal cartilage grafting offers superior durability, with meta-analyses showing 92-98% closure rates versus 82-88% for fascia graft .(3) Full-thickness cartilage (>1.5 mm), however, risks acoustic mass-loading, worsening high-frequency hearing by 8-12 dB at 4 kHz.(4) Partial-thickness slicing (0.4-0.6 mm) maintains strength while enhancing sound transmission, as shown in clinical series.(5) Endoscopic approaches further improve visualization and reduce operative trauma.(6) No randomized trials compare sliced versus full-thickness tragal cartilage in adult endoscopic tympanoplasty.(7,8) This pilot study fills that gap, optimizing technique for local needs before
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| endoscope | Device | endoscopic type 1 tympano plasty |
|
| Measure | Description | Time Frame |
|---|---|---|
| Outcome of partial-thickness vs full-thickness tragal cartilage grafts in endoscopic type 1 tympanoplasty in adults. | Outcome of partial-thickness vs full-thickness tragal cartilage grafts in endoscopic type 1 tympanoplasty in adults. | baseline |
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Inclusion Criteria:
Exclusion Criteria:
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Inclusion (all required):
Exclusion criteria :
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Monica Gamil Tawfiq | Contact | 01270882995 | gamilmonica25@gmail.com | |
| Ezzat Mohamed Saleh, Prof | Contact | 01006722404 | ezzatsaleh@aun.edu.eg |
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| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 15273542 | Background | Dindo D, Demartines N, Clavien PA. Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann Surg. 2004 Aug;240(2):205-13. doi: 10.1097/01.sla.0000133083.54934.ae. | |
| 9395344 | Background | Rizer FM. Overlay versus underlay tympanoplasty. Part II: the study. Laryngoscope. 1997 Dec;107(12 Pt 2):26-36. doi: 10.1097/00005537-199712001-00002. |
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| ID | Term |
|---|---|
| D019723 | Endoscopes |
| D014433 | Tympanoplasty |
| ID | Term |
|---|---|
| D019719 | Diagnostic Equipment |
| D004864 | Equipment and Supplies |
| D013523 | Surgical Equipment |
| D013506 | Otologic Surgical Procedures |
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| D013517 | Otorhinolaryngologic Surgical Procedures |
| D013514 | Surgical Procedures, Operative |