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| ID | Type | Description | Link |
|---|---|---|---|
| PH/IRB/2025/023 | Other Identifier | Patel Hospital |
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Postoperative pain after laparoscopic cholecystectomy remains clinically relevant. This double-blinded randomized controlled trial compares the analgesic efficacy of landmark-guided Erector Spinae Plane Block (ESPB) and subcostal transversus abdominis plane (STAP) block in 60 adult patients. Postoperative pain will be evaluated using the Visual Analogue Scale at multiple time points, along with rescue analgesic requirements and time to first analgesic request, to assess the effectiveness of these techniques in resource-limited settings.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Experimental: Landmark-guided Erector Spinae Plane Block | Experimental | Patients will receive a landmark-guided erector spinae plane block on the right side at the T9 level with 30 mL of 0.25% ropivacaine after induction of general anesthesia. |
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| landmark-guided Subcostal Transversus Abdominis Plane Block | Active Comparator | Patients will receive a landmark-guided Subcostal Transversus Abdominis Plane Block on the right side with 30 mL of 0.25% ropivacaine after induction of general anesthesia. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Landmark guided Erector Spinae Block | Drug | Patients will receive a landmark-guided Erector Spinae Plane Block on the right side at T9 level with 30 mL of 0.25% ropivacaine after induction of general anesthesia. |
| Measure | Description | Time Frame |
|---|---|---|
| VAS score | Postoperative pain intensity measured using the Visual Analog Scale (VAS), a 10-cm scale ranging from 0 to 10, where 0 = no pain and 10 = worst imaginable pain. Higher scores indicate worse pain. | From arrival in the post-anesthesia care unit (PACU) through 24 hours postoperatively, assessed at 30 minutes in PACU, and at 6 hours, 12 hours, and 24 hours after surgery. |
| Measure | Description | Time Frame |
|---|---|---|
| need for rescue analgesia and time for first analgesic request. | Proportion of patients requiring rescue analgesia during the postoperative period. | From completion of surgery through 24 hours postoperatively. |
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INCLUSION CRITERIA:
EXCLUSION CRITERIA:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Kulsoom Mehmood | Karachi | Pakistan |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 31333385 | Background | Vadera HK, Mistry T. Erector spinae plane block: Anatomical landmark-guided technique. Saudi J Anaesth. 2019 Jul-Sep;13(3):268-269. doi: 10.4103/sja.SJA_780_18. No abstract available. | |
| 32317901 | Background | Dey S, Mistry T, Mittapalli J, Neema PK. Landmark guided continuous erector spinae plane block: An adjunct for perioperative analgesia in a patient with difficult back operated for total hip arthroplasty. Saudi J Anaesth. 2020 Apr-Jun;14(2):276-277. doi: 10.4103/sja.SJA_46_20. Epub 2020 Mar 5. No abstract available. |
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| Type | Includes Protocol | Includes SAP | Includes ICF | Document Label | Document Date | Document Uploaded Date | Document File Name |
|---|---|---|---|---|---|---|---|
| Prot_SAP | Yes | Yes | No | Study Protocol and Statistical Analysis Plan | Feb 24, 2026 |
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| Landmark guided Transversus Abdominis Plane Block | Drug | Patients will receive a landmark-guided Subcostal Transversus Abdominis Plane Block on the right side with 30 mL of 0.25% ropivacaine after induction of general anesthesia. |
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| 33032124 | Background | Saadawi M, Layera S, Aliste J, Bravo D, Leurcharusmee P, Tran Q. Erector spinae plane block: A narrative review with systematic analysis of the evidence pertaining to clinical indications and alternative truncal blocks. J Clin Anesth. 2021 Feb;68:110063. doi: 10.1016/j.jclinane.2020.110063. Epub 2020 Oct 5. |
| 30886130 | Background | Kot P, Rodriguez P, Granell M, Cano B, Rovira L, Morales J, Broseta A, Andres J. The erector spinae plane block: a narrative review. Korean J Anesthesiol. 2019 Jun;72(3):209-220. doi: 10.4097/kja.d.19.00012. Epub 2019 Mar 19. |
| 34085883 | Background | Ozdemir H, Araz C, Karaca O, Turk E. Comparison of Ultrasound-Guided Erector Spinae Plane Block and Subcostal Transversus Abdominis Plane Block for Postoperative Analgesia after Laparoscopic Cholecystectomy: A Randomized, Controlled Trial. J Invest Surg. 2022 Apr;35(4):870-877. doi: 10.1080/08941939.2021.1931574. Epub 2021 Jun 4. |
| 30851501 | Background | Altiparmak B, Korkmaz Toker M, Uysal AI, Kuscu Y, Gumus Demirbilek S. Ultrasound-guided erector spinae plane block versus oblique subcostal transversus abdominis plane block for postoperative analgesia of adult patients undergoing laparoscopic cholecystectomy: Randomized, controlled trial. J Clin Anesth. 2019 Nov;57:31-36. doi: 10.1016/j.jclinane.2019.03.012. Epub 2019 Mar 6. |
| 29913392 | Background | Tulgar S, Kapakli MS, Senturk O, Selvi O, Serifsoy TE, Ozer Z. Evaluation of ultrasound-guided erector spinae plane block for postoperative analgesia in laparoscopic cholecystectomy: A prospective, randomized, controlled clinical trial. J Clin Anesth. 2018 Sep;49:101-106. doi: 10.1016/j.jclinane.2018.06.019. Epub 2018 Jun 15. |
| 35550031 | Background | Kapukaya F, Ekinci M, Ciftci B, Atalay YO, Golboyu BE, Kuyucu E, Demiraran Y. Erector spinae plane block vs interscalene brachial plexus block for postoperative analgesia management in patients who underwent shoulder arthroscopy. BMC Anesthesiol. 2022 May 12;22(1):142. doi: 10.1186/s12871-022-01687-5. |
| 31677656 | Background | Chin KJ, Pawa A, Forero M, Adhikary S. Ultrasound-Guided Fascial Plane Blocks of the Thorax: Pectoral I and II, Serratus Anterior Plane, and Erector Spinae Plane Blocks. Adv Anesth. 2019 Dec;37:187-205. doi: 10.1016/j.aan.2019.08.007. Epub 2019 Sep 13. No abstract available. |
| 27501016 | Background | Forero M, Adhikary SD, Lopez H, Tsui C, Chin KJ. The Erector Spinae Plane Block: A Novel Analgesic Technique in Thoracic Neuropathic Pain. Reg Anesth Pain Med. 2016 Sep-Oct;41(5):621-7. doi: 10.1097/AAP.0000000000000451. |
| 29628547 | Background | Ramkiran S, Jacob M, Honwad M, Vivekanand D, Krishnakumar M, Patrikar S. Ultrasound-guided Combined Fascial Plane Blocks as an Intervention for Pain Management after Laparoscopic Cholecystectomy: A Randomized Control Study. Anesth Essays Res. 2018 Jan-Mar;12(1):16-23. doi: 10.4103/aer.AER_157_17. |
| 34340839 | Background | Canitez A, Kozanhan B, Aksoy N, Yildiz M, Tutar MS. Effect of erector spinae plane block on the postoperative quality of recovery after laparoscopic cholecystectomy: a prospective double-blind study. Br J Anaesth. 2021 Oct;127(4):629-635. doi: 10.1016/j.bja.2021.06.030. Epub 2021 Jul 31. |
| Feb 23, 2026 |
| Prot_SAP_000.pdf |
| ICF | No | No | Yes | Informed Consent Form | Feb 24, 2026 | Feb 23, 2026 | ICF_001.pdf |