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This study aims to compare the effectiveness of extracorporeal shock wave therapy (ESWT) versus structured therapeutic exercise in patients with chronic knee osteoarthritis (KOA), with respect to pain reduction and improvement of knee function.
Knee osteoarthritis (KOA) is a highly prevalent chronic degenerative joint disease characterized by progressive cartilage loss, chronic pain, stiffness, functional disability, and reduced quality of life in adults, particularly the elderly.
Extracorporeal shock wave therapy (ESWT) has emerged as a non-invasive physical modality that delivers acoustic pressure waves to musculoskeletal tissues, stimulating biological responses such as enhanced microcirculation, anti-inflammatory cytokine modulation, neovascularization, cartilage and bone repair processes, and decreased pain transmission.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| ESWT Group | Experimental | Patients will receive extracorporeal shock wave therapy. |
|
| Exercise Therapy Group | Active Comparator | Patients will undergo a structured exercise therapy program. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Extracorporeal shock wave therapy | Other | Patients will receive extracorporeal shock wave therapy. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Change in pain intensity | Change in pain intensity will be assessed using the Visual Analogue Scale (VAS) which is a 10-cm horizontal line used to measure pain intensity, ranging from (0) "no pain" to (10) "worst imaginable pain". | 5-week after intervention |
| Measure | Description | Time Frame |
|---|---|---|
| Stiffness assessment | Stiffness will be assessed using the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). WOMAC will be recorded at baseline, at the end of the intervention period, and during follow-up. Higher scores indicate greater symptom severity. | 5-week after intervention |
| Assessment of physical function |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Magdy M Shabana, MD | Contact | 00201006053332 | magdy.shabana@giu-uni.de |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| German International University | Recruiting | Cairo | 12613 | Egypt |
The data will be available upon a reasonable request from the corresponding author after the end of study for one year.
After the end of study for one year.
The data will be available upon a reasonable request from the corresponding author.
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| ID | Term |
|---|---|
| D000074059 | Extracorporeal Shockwave Therapy |
| ID | Term |
|---|---|
| D014464 | Ultrasonic Therapy |
| D003972 | Diathermy |
| D006979 | Hyperthermia, Induced |
| D013812 | Therapeutics |
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| Exercise therapy program | Other | Patients will undergo a structured exercise therapy program. |
|
Physical function will be assessed using the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). WOMAC will be recorded at baseline, at the end of the intervention period, and during follow-up. Higher scores indicate greater symptom severity. |
| 5-week after intervention |
| Knee range of motion | Knee range of motion (ROM) will be assessed. | 5-week after intervention |
| Incidence of adverse events | Incidence of adverse events will be recorded. | 5-week after intervention |
| D026741 |
| Physical Therapy Modalities |
| D012046 | Rehabilitation |