PRIME Mothers is a national observational trial designed to evaluate patient outcomes with Stratamark® for the prevention of stretch marks during pregnancy and the postpartum period. The study is designed to fit seamlessly into routine clinical practice, with digital follow-up and home resupply, minimising clinic involvement.

Pregnant women visiting the healthcare professional will have the opportunity to participate in the study by scanning a QR code displayed at the healthcare professional office. Upon scanning the QR code, participants will be directed to complete an electronic informed consent form, followed by a baseline self-assessment. Eligibility will be automatically determined based on the information provided during this assessment. As part of the baseline self-assessment, participants will submit demographic information and confirm the absence of any pre-existing stretch marks on their abdomen. Eligible participants will then receive a confirmation notification indicating their enrollment in the study. This notification must be presented to the healthcare professional to receive the initial supply (two tubes of 50g Stratamark®) of the study product from the healthcare professionals office

Monthly follow-up self-assessments will be performed remotely using an electronic Case Report Form (eCRF) tool. Participants will receive a link to access and complete the survey online, this includes the option to provide photographs (abdomen only).

If a participant requires resupply of the study product, completion of at least one monthly follow-up self-assessment is required. Upon completion, the participant will receive a confirmation notification containing a code and a link to order the next product supply free of charge.

The final assessment will take place 6-8 weeks after the baby has been delivered.

Inclusion Criteria:

• Pregnant women at any gestational age.
• Participants who are in good health, including those that are carrying multiples, who are 18 years of age or older.
• Confirmed absence of pre-existing stretch marks on the abdomen.
• Agree to apply Stratamark according to the prescribed protocol for the duration of the study.
• Ability to complete remote online surveys via an electronic device.
• Provide signed informed consent to participate in the study.

Exclusion Criteria:

• Visible stretch marks on the abdomen prior to enrollment.
• Pre-existing skin conditions (e.g., eczema, psoriasis), on the abdomen that could interfere with product application or assessment of stretch marks.
• Known hypersensitivity or allergy to any of the ingredients in Stratamark.
• Use of other topical treatments on the abdomen, including but not limited to oils, or creams targeting stretch mark prevention.
• Participants unable to give informed consent, or unable to have written consent provided on their behalf.
• Participants who cannot administer the treatment or have the treatments administered as per the directions for use.

Women

Healthy pregnant women at any gestational age, who are at least 18 years of age and do not have visible stretch marks on the abdomen prior to enrolment.