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In cases with breast masses, Doppler resistive index values will be calculated for the mass and surrounding healthy tissue and the opposite healthy breast tissue, and their effect on distinguishing between benign and malignant masses will be evaluated.
The aim of this study is to reveal the role of differences in the resistive index of masses and surrounding tissue in distinguishing between benign and malignant masses using a new approach in the evaluation of breast masses with Doppler ultrasound. The minimum, maximum, and average RI values obtained from the mass and healthy breast tissue will be recorded. The relative RI value difference will be calculated from the RI values of the mass and healthy tissue. Based on the pathology results, the cases will be divided into two groups: benign and malignant. The threshold values of these values in malignant and benign masses will be determined and compared. Additionally, vascular index values in breast masses will be calculated and compared using the relatively new Doppler Microvascular Flow method.
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| Measure | Description | Time Frame |
|---|---|---|
| A Novel Approach to the Evaluation of Breast Masses Using Doppler Ultrasonography: Percentage Changes in Resistive Index Between the Mass and Surrounding Normal Parenchyma in Benign-Malignant Differentiation | ROC curve analysis will be applied for the diagnostic performance of relative RI change in benign and malignant lesions. | 3-4 months |
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Inclusion Criteria:
Exclusion Criteria:
Since this study is a breast study, it will only be conducted on women.
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The study population will consist of female patients over the age of 18 who underwent breast biopsy in the radiology department due to a solid lesion in the breast.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Ahmet Yeşildağ, Prof.Dr | Contact | +905057728297 | ahmetysd@hotmail.com | |
| Gökçe Merve Arman, Dr. | Contact | +905058734762 | gmerveturgut@gmail.com |
| Name | Affiliation | Role |
|---|---|---|
| Ahmet Yeşildağ, Prof.Dr. | Karamanoğlu Mehmetbey Universty | Study Director |
| Ahmet Yeşildağ, Prof.Dr. | Karamanoğlu Mehmetbey University | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Karamanoğlu Mehmetbey University, KEAH | Recruiting | Karaman | Lütfen Seçiniz. | 70200 | Turkey (Türkiye) |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 10665344 | Background | Choi HY, Kim HY, Baek SY, Kang BC, Lee SW. Significance of resistive index in color Doppler ultrasonogram: differentiation between benign and malignant breast masses. Clin Imaging. 1999 Sep-Oct;23(5):284-8. doi: 10.1016/s0899-7071(99)00152-7. | |
| 31535669 | Background | Niu J, Ma J, Guan X, Zhao X, Li P, Zhang M. Correlation Between Doppler Ultrasound Blood Flow Parameters and Angiogenesis and Proliferation Activity in Breast Cancer. Med Sci Monit. 2019 Sep 19;25:7035-7041. doi: 10.12659/MSM.914395. |
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| 11014252 | Background | Mehta TS, Raza S, Baum JK. Use of Doppler ultrasound in the evaluation of breast carcinoma. Semin Ultrasound CT MR. 2000 Aug;21(4):297-307. doi: 10.1016/s0887-2171(00)90024-6. |