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Cesarean section (CS) is one of the most frequently performed surgical procedures globally, with an increasing demand for safe and effective anesthesia techniques. Regional anesthesia, particularly intrathecal anesthesia, has become the method of choice for elective cesarean deliveries.The most commonly used local anesthetic for intrathecal anesthesia is bupivacaine.Recent studies have focused on adjunctive agents to enhance the efficacy of local anesthetics.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Group (B) | Active Comparator | will receive intra-thecal hyperbaric bupivacaine 11 mg(2.2 ml) of 0.5% bupivacaine, with 0.5 ml of normal saline in total volume 2.5 ml. |
|
| Group (BD) | Active Comparator | will receive 9 mg (1.8 ml) of 0. 5% bupivacaine, with 5 μg of DEX in 0.5ml of normal saline in total volume 2.5 ml. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Bupivacaine | Drug | patient will receive intra-thecal hyperbaric bupivacaine 11 mg(2.2 ml) of 0.5% bupivacaine, with 0.5 ml of normal saline in total volume 2.5 ml. |
|
| Measure | Description | Time Frame |
|---|---|---|
| the duration of sensory block | time taken from intrathecal injection to sensory regression to S1 dermatome. | after anesthesia up to 12 hours postoperatively |
| Measure | Description | Time Frame |
|---|---|---|
| the onset time of sensory block | time taken from intrathecal injection to the maternal feeling of lower extremities temperature increment or numbness | during 30 minutes after intrathecal injection |
| the onset time of motor block |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| fatma ahmed abdelfatah, MD | Contact | 00201091921540 | drfatmaahmed86@gmail.com |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Banha Faculity of Medicine | Recruiting | Banhā | Elqalyoubea, | 13511 | Egypt |
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| ID | Term |
|---|---|
| D002045 | Bupivacaine |
| D020927 | Dexmedetomidine |
| ID | Term |
|---|---|
| D000813 | Anilides |
| D000577 | Amides |
| D009930 | Organic Chemicals |
| D000814 | Aniline Compounds |
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| Bupivacaine and Dexmedetomidine | Drug | patient will receive 9 mg (1.8 ml) of 0. 5% bupivacaine, with 5 μg of DEX in 0.5ml of normal saline in total volume 2.5 ml. |
|
time taken from intrathecal injection to MBS > 1
| during 30 minutes after intrathecal injection |
| The recovery quality of parturients | ObsQoR-11, score from 0 to 10 in each term, where 0 = strongly agree and 10 = strongly disagree, the higher of the score, the higher of recovery quality | 24 hours post-operatively |
| D000588 |
| Amines |
| D007093 | Imidazoles |
| D001393 | Azoles |
| D006573 | Heterocyclic Compounds, 1-Ring |
| D006571 | Heterocyclic Compounds |