Basic and Clinical Research of Pregnancy-Induced Hyperten... | NCT07464379

Studies
Basic and Clinical Research of Pregnancy-Induced Hypertension

NCT07464379

Sponsor

Second Affiliated Hospital of Wenzhou Medical University

Status

Recruiting

Last Update Posted

Mar 11, 2026Actual

Enrollment

100Estimated

Phase

Not provided

Conditions

Pregnancy-induced Hypertension

Interventions

no Intervention

Countries

China

Protocol Section

Identification Module Status Module Sponsor/Collaborators Module Oversight Module Description Module Conditions Module Design Module Arms/Interventions Module Outcomes Module Eligibility Module Contacts/Locations Module References Module IPD Sharing Statement Module

Results Section

Participant Flow Module Baseline Characteristics Module Outcome Measures Module Adverse Events Module More Info Module

Annotation Section

Annotation Module

Document Section

Large Document Module

Derived Section

Miscellaneous Info Module Condition Browse Module Intervention Browse Module

Protocol Section

Identification Module

NCT ID

Results Section

No data available

No data is available for this block.

Annotation Section

No data available

No data is available for this block.

Document Section

No data available

No data is available for this block.

Derived Section

Miscellaneous Info Module

Version Holder

Status Module

Record Verification Date

Mar 2026

Overall Recruitment Status or Expanded Access Status

Recruiting

Last Known Status

Not provided

Delayed Posting

Not provided

Why Stopped

Not provided

Expanded Access Info

Start Date

Jan 1, 2020Actual

Primary Completion Date

Dec 31, 2027Estimated

Completion Date

Dec 31, 2028Estimated

First Submitted Date

Jan 5, 2026

First Submission Date that Met QC Criteria

Mar 10, 2026

First Posted Date

Mar 11, 2026Actual

Results Waived

Not provided

Results First Submitted Date

Not provided

Results First Submitted that Met QC Criteria

Not provided

Results First Posted Date

Not provided

Certification/Extension (aka Delayed Results) First Submitted Date

Not provided

Certification/Extension First Submitted that Passed QC Review

Not provided

Certification/Extension First Posted Date

Not provided

Last Update Submitted Date

Mar 10, 2026

Last Update Posted Date

Mar 11, 2026Actual

Oversight Module

Has Data Monitoring Committee (DMC)

Not provided

Is FDA Regulated Drug

Is FDA Regulated Device

Is Unapproved Device

Not provided

Pediatric Postmarket Surveillance of a Device Product

Not provided

Product Exported from US

Not provided

FDAAA801 Violation

Not provided

Description Module

Brief Summary

Collect blood pressure, blood, amniotic fluid, placenta and other samples from normal pregnant women, patients with pregnancy-induced hypertension and those who have experienced miscarriage, and conduct tests on them.

Detailed Description

Not provided

Design Module

Study Type

Observational

Number of References to an Expanded Access Study

Not provided

Expanded Access Types

Not provided

Patient Registry

Target Follow-Up Duration

Not provided

Phases

Not provided

Interventional Study Design

Allocation

Not provided

Intervention Model

Biospecimen

No data available

No data is available for this block.

Enrollment

100Estimated

Arms/Interventions Module

Arm Groups

Label	Type	Description	Intervention Names
control group		Healthy pregnant women	Other: no Intervention
PIH group		Pregnancy-induced hypertension patients	Other: no Intervention

Interventions

Name	Type	Description	Arm Group Labels	Other Names
no Intervention	Other	observation	PIH group control group

Outcomes Module

Primary Outcomes

Measure	Description	Time Frame
PIH	the content of GPR18 type macrophages	Early pregnancy：Weeks 1 to 12 (the first to third months of pregnancy) ；mid-pregnancy：Weeks 13 to 27 (the 4th to 6th month of pregnancy) ；post-delivery period：Weeks 28 to 40 (the 7th to 9th months of pregnancy)；the day of delivery。

Secondary Outcomes

Measure	Description	Time Frame
PIH	Blood pressure	delivery
PIH	SPM content	delivery

Other Outcomes

Not provided

Eligibility Module

Eligibility Criteria

Inclusion Criteria:

- Healthy pregnant women, patients with miscarriage, etc.

Exclusion Criteria:

Heart disease, infections, etc. in pregnant women Uncooperative patients

Accepts Healthy Volunteers

Yes

Sex

Female

Sex/Gender Based

Not provided

Sex/Gender Description

Not provided

Minimum Age

20 Years

Maximum Age

50 Years

Standard Ages

Adult

Study Population

Healthy parturient women, women who have had miscarriages, patients with pregnancy-induced hypertension

Sampling Method

Non-Probability Sample

Contacts/Locations Module

Central Contacts

Name	Role	Phone	Extension	Email
Qian Wang, PHD	Contact	13587638653		wqian84@163.com

Overall Officials

Name	Affiliation	Role
Qian Wang	The Second Affiliated Hospital of wenzhou Medical University Longwan Branch	Study Chair

Locations

Facility	Status	City	State	ZIP	Country	Contacts
The Second Affiliated Hospital of Wenzhou Medical University	Recruiting	Wenzhou	Zhejiang	325000	China

IPD Sharing Statement Module

Plan to Share IPD

Description

Not provided

Types

Not provided

Time Frame

Not provided

Access Criteria

Not provided

URL

Not provided

Condition Browse Module

MeSH Terms

ID	Term
D046110	Hypertension, Pregnancy-Induced

Ancestor Terms

ID	Term
D011248	Pregnancy Complications
D005261	Female Urogenital Diseases and Pregnancy Complications
D000091642	Urogenital Diseases
D006973	Hypertension

Browse Leaves

Not provided

Browse Branches

Not provided