Evaluation of Bile Acid Concentrations and Their Signaling as Markers of Testicular Tumorigenesis and Germ Cell Tumor Chemosensitivity

Evaluation of Bile Acid Concentrations and Their Signaling as Markers of Testicular Tumorigenesis and Germ Cell Tumor Chemosensitivity (TG-BIL)

This is a study exploring measurable markers in the blood of patients with testicular tumors. The investigators will focus on the importance of measuring and analyzing these markers for their prognostic value and predictive response to treatment.

Inclusion Criteria:

• Adult patient, male, with a clinical and biological diagnosis of germ cell tumor of the testis in pre-orchidectomy, at the stage of the disease and any histological subtype of germ cell tumor
• Affiliation with a Social Security organization
• Able to give informed consent to participate in the research.

Exclusion Criteria:

• Patient with a hepatobiliary pathology
• Patient treated with Colestyramine
• Patient who has undergone cholecystectomy or extensive resection of the small intestine
• Patient deprived of liberty
• Patient under guardianship, curatorship, or legal protection
• Patient unable to understand the protocol (language barrier, cognitive difficulties)
• Patient with another active cancer
• Patient participating in a therapeutic clinical trial
• Refusal to participate