This randomized controlled trial evaluates the effectiveness of a simulation-based multidisciplinary team training program on the management of Local Anesthetic Systemic Toxicity (LAST) among non-anesthesiologist surgical residents. Guided by Kirkpatrick's evaluation model, the study investigates improvements in knowledge, technical and non-technical skills, and the retention of these competencies one month after training

Local Anesthetic Systemic Toxicity (LAST) is a rare but potentially life-threatening complication of regional anesthesia. Advances in ultrasound-guided blocks have reduced its incidence, yet LAST remains a major concern due to severe cardiovascular and neurological risks. The American Society of Regional Anesthesia and Pain Medicine (ASRA) recommends early lipid emulsion therapy and emphasizes proper training. Simulation-based multidisciplinary training provides a dynamic and immersive experience, improving both technical and behavioral skills. This trial applies Kirkpatrick's four-level model (reaction, learning, behavior, results) to assess the training program. Primary endpoint: improvement in knowledge test scores. Secondary endpoints: OSCE performance, satisfaction, and key performance indicators related to simulated LAST management.

Inclusion Criteria:

1. Surgical residents (General Surgery, Orthopedics, Obstetrics & Gynecology, Dentistry) on active rotation at Selçuk University Faculty of Medicine.
2. Voluntary participation with written informed consent.
3. No prior comprehensive LAST training in the last 12 months.

Exclusion Criteria:

1. Prior comprehensive LAST training or instructor experience in the last 12 months.
2. Anesthesiology residents or specialists.
3. Unable to complete follow-up due to rotation change or leave.
4. Declining or withdrawing consent.

De-identified individual participant data will be made available from the corresponding author upon reasonable request after publication of the article.

1 year