Veteran's Interdisciplinary Care for Traumatic Brain Injury and Co-Occurring Disorders Rehabilitation Trial

Veteran's Interdisciplinary Care for Traumatic Brain Injury & Co-Occurring Disorders Rehabilitation Trial - A Pragmatic, Randomized, Controlled Clinical Trial

The goal of this clinical trial is to learn if the Avalon Action Alliance Interdisciplinary Outpatient Rehabilitation Program (IORP) can reduce long-lasting symptoms of traumatic brain injury (TBI) and co-occurring disorders in veterans and first responders. The main questions it aims to answer are:

• Does a 3-week IORP reduce symptoms of long-lasting TBI and co-occurring disorders in military veterans and first responders?
• Does the 3-week IORP improve life quality and function in military veterans and first responders?

Researchers will compare the Control group to the Invention group to see if a 3-week of IORP reduced symptoms of TBI and co-occurring disorders in military veterans and first responders.

Participants will complete the following activities. The items with an asterisk(*) are not required or available at all sites.

• Answer online survey questions about their TBI symptoms, life satisfaction, and life activities
• Complete two blood draws*
• Complete two magnetic resonance imaging (MRI) brain scans*

Inclusion Criteria:

• Meets general eligibility requirements for site specific 3-week IORP
• Capable of providing informed consent for IORP and study participation
• English speaking
• 18 to 65 years old

Exclusion Criteria:

• History of TBI of any severity in the past 6 months
• Active substance use disorder that precludes study participation
• Neurologic, psychiatric, or other medical condition that would prohibit full study participation
• Active-duty military service member
• Any other circumstance that, in the opinion of the investigator, would undermine the integrity or success of the project