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The investigators are conducting an observational trial examining young women over the course of 28 days in which we are monitoring movement, sleep, heart rate, oxygen saturation, gut physiology, light, and menstrual cycle. The inter- and independence of the cyclicity of these variables with each other, the circadian cycle, the menstrual cycle, and the sleep cycle will be tested.
For 28 days, women will wear devices to capture: ambient light exposure, lower limb biomechanics, sleep, oxygen saturation, heart rate, temperature, and gut physiology.
Twice during the study, women will have saliva collected for 7 hours under dim light conditions in order to determine melatonin concentrations. During this 7-hour period, two blood draws for determination of proteomic profiles will also occur.
Daily urine samples will be tested for LH until the presence of the LH surge to help identify menstrual phase.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Women | Young women with regular menstrual cycles |
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| Measure | Description | Time Frame |
|---|---|---|
| Stride time | Duration of each stride | 28 days |
| Measure | Description | Time Frame |
|---|---|---|
| Sleep | Daily sleep duration determined through actigraphy | 28 days |
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Inclusion Criteria:
Exclusion Criteria:
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Healthy young women with erratic schedules
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Lara Weed, BS, MS | Contact | 650-723-2300 | weed@stanford.edu |
| Name | Affiliation | Role |
|---|---|---|
| Jamie M Zeitzer, PhD | Stanford University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Stanford University | Recruiting | Stanford | California | 94305 | United States |
Deidentified data will be provided via Dryad, analytic code will be provided via Github
IPD and supporting information will be made available after publication for an indefinite amount of time
Both Dryad and Github are fully open access
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| ID | Term |
|---|---|
| D021081 | Chronobiology Disorders |
| ID | Term |
|---|---|
| D009422 | Nervous System Diseases |
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Blood samples