Exercise in Patients Undergoing Autologous Stem Cell Transplantation: A Randomized Controlled Trial

The Effect of Therapeutic Exercise in Patients Undergoing Autologous Stem Cell Transplantation: A Randomized Controlled Trial

This interventional study assigns participants undergoing autologous hematopoietic stem cell transplantation to a supervised exercise program or usual care. The exercise program includes strength, endurance, and flexibility sessions for 8 weeks, 5 days per week. The control group receives usual care without a structured exercise program.

This interventional study is conducted at Erciyes University Faculty of Medicine, Department of Hematology in patients scheduled for autologous hematopoietic stem cell transplantation. Eligible participants are assigned to either a supervised exercise program or usual care.

The exercise intervention consists of strength, endurance, and flexibility sessions performed five days per week for eight weeks under supervision. Participants in the control group receive standard medical care without a structured exercise program.

The study aims to examine the effects of the exercise program during the transplantation process in patients undergoing autologous stem cell transplantation.

Inclusion Criteria:

• Age ≥ 18 years, <65 years
• Able to exercise at time of enrolment.
• no methastasis

Exclusion Criteria:- Unable to communicate or read in Turkish,

• Contraindications to 3 T MRI (e.g., pacemaker or implanted metallic device).
• co-morbid cardiac disease
• painful joint