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This research aims to explore the relative efficacy of Verbal-only and GVT on naming difficulty in Cantonese-speaking people with aphasia (PWA).
The primary research question in this study is: "For Cantonese-speaking people with aphasia, what are the relative effects of verbal treatment compared to gesture plus verbal treatment (GVT) on verbal and gesture naming at different levels?"
People with aphasia will be engaged in a repeated measures experimental design. Participants will be engaged in two phases of training. In the first phase, participants will be assigned to receive verbal-only treatment. To minimize and prevent the carry-over effects caused by the first intervention, a one-month washout period will be implemented before the start of the second phase. After a washout period, participants will switch to GVT in the second phase.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Verbal-only | Active Comparator | This is a within-subject comparison study where each participant receives both interventions sequentially. During the first phase, participants receive verbal-only therapy (VT). In the subsequent phase, they receive Gesture verbal treatment (GVT). The order of interventions is fixed, and each participant acts as their own control to compare the effects of the two interventions. |
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| Gesture plus Verbal | Active Comparator | This is a within-subject comparison study where each participant receives both interventions sequentially. During the first phase, participants receive verbal-only therapy (VT). In the subsequent phase, they receive Gesture verbal treatment (GVT). The order of interventions is fixed, and each participant acts as their own control to compare the effects of the two interventions. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Verbal treatment | Behavioral | This study will involve the following naming interventions: 1) Semantic Features Analysis, 2) Modified Ortho-phonological cueing therapy and Phonological Component Analysis, and 3) Repetition with Cueing Hierarchy. |
| Measure | Description | Time Frame |
|---|---|---|
| Changes in the scores of the Naming Probes | The treatment effects on naming will be assessed through verbal naming and gesture production using the black and white drawing naming task. Responses will be counted as correct if they can be identified by the rater as the target word in verbal naming and convey the depicted concept through gesture production, even if the articulation or hand and arm movements are slightly distorted. | From enrollment to the end of treatment at 4 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Changes in the scores of the Cantonese Aphasia Battery | The Cantonese Aphasia Battery was conducted to evaluate improvements in various linguistic measures (e.g., question comprehension, step commands, repetition, etc.). The minimum and maximum values are 0 and 100, respectively, with higher scores indicating a better outcome. | From enrollment to the end of treatment at 4 weeks |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Annie Zhiyao Hu | Contact | 852-6068-8312 | annie920@connect.hku.hk |
| Name | Affiliation | Role |
|---|---|---|
| Anthony Pak Hin Professor Kong | The University of Hong Kong | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| The University of Hong Kong | Recruiting | Hong Kong | Hong Kong |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| Background | Yiu, E. M-L. (1992). Linguistic assessment of Chinese-speaking aphasics: Development of a Cantonese aphasia battery. Journal of Neurolinguistics, 7(4), 379-424. https://doi.org/10.1016/0911-6044(92)90025-R | ||
| Background | Lau, S. W. -H. (2001). The Cantonese FACS feasibility with aphasic patients in Hong Kong. Unpublished bachelor dissertation, The University of Hong Kong, Hong Kong. | ||
| Background | Kong, A. P.-H., & Wang, C. (2016). Main concept analysis (MCA) for oral discourse production. In. Hong Kong: The Commercial Press H.K Ltd. | ||
| Background | Kong, A. P.-H., & Ng, C. Y.-T. (2022). Psycholinguistic Considerations for Adapting the Cantonese Version of Comprehensive Aphasia Test (Cant-CAT): A Feasibility Study. Perspectives of the ASHA Special Interest Groups, 7(4), 1211-1222. https://doi.org/doi:10.1044/2022_PERSP-22-00044 | ||
| 19382013 |
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According to the consent form approved by HREC, any information obtained in this study will remain strictly confidential (except as required by relevant legal authorities), and will be used for research purposes and clinical education use only. Videos, verbatim transcripts, and data will be uploaded to TalkBank Consortium (talkbank.org), allowing authorized researchers and educators from other institutions to view, analyze, and compare the data.
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| ID | Term |
|---|---|
| D001037 | Aphasia |
| D005868 | Gestures |
| ID | Term |
|---|---|
| D013064 | Speech Disorders |
| D007806 | Language Disorders |
| D003147 | Communication Disorders |
| D019954 | Neurobehavioral Manifestations |
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Participants will be engaged in two phases of training. In the first phase, participants will be assigned to receive verbal-only treatment. To minimize and prevent the carry-over effects caused by the first intervention, a one-month washout period will be implemented before the start of the second phase. After a washout period, participants will switch to GVT in the second phase.
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| Gesture plus verbal treatment | Behavioral | This study will involve the following interventions: 1) Combined Semantic and Gesture treatment, 2) Combined Phonological and Gesture treatment, and 3) Combined Repetition and Gesture treatment. |
|
| Changes in the scores of the Comprehensive Aphasia Test | The Comprehensive Aphasia Test will be conducted to evaluate improvements in various cognitive and linguistic measures (e.g., semantic memory, word fluency, auditory comprehension, etc.). There are different subtests in the assessment, with a minimum value of 0, and maximum values ranging from 70 to 130, with higher scores indicating a better outcome. | From enrollment to the end of treatment at 4 weeks |
| Changes in the scores of the Cantonese Boston Naming Test | The Cantonese Boston Naming Test will be conducted to evaluate the generalization effects on naming ability. The minimum and maximum values are 0 and 30, respectively, with higher scores indicating a better outcome. | From enrollment to the end of treatment at 4 weeks |
| Changes in the number of main concepts and gestures in discourse production tasks | Discourse samples were collected from participants through various monologues. The discourse elicitation tasks included Main concept analysis, procedural (Ham and Egg Sandwich), narrative (Telling of the story "Tortoise and Hare"), and personal narrative (Sharing of an important event). This will help in assessing their word retrieval abilities at both the sentence and discourse levels, and their verbal and non-verbal communication skills in realistic contexts. Regarding discourse assessment, all samples will be video recorded using a camera. After that, the samples will undergo discourse analysis based on Chinese Linguistics Communication Measures, where conversational speech will be transcribed, and the linguistic index will be calculated and compared. Finally, the number of various types of gestures will also be computed and compared. | From enrollment to the end of treatment at 4 weeks |
| Changes in the scores of the Functional Communication questionnaire | Improvements in functional communication will be evaluated using the Functional Assessment of Communication Skills questionnaire. There are different subtests in the assessment, with minimum values of 0, and maximum values ranging from 35 to 147, with higher scores indicating a better outcome. | From enrollment to the end of treatment at 4 weeks |
| Background |
| Kong AP, Law SP. A linguistic communication measure for monitoring changes in Chinese aphasic narrative production. Clin Linguist Phon. 2009 Apr;23(4):255-69. doi: 10.1080/02699200802673234. |
| 14751006 | Background | Cheung RW, Cheung MC, Chan AS. Confrontation naming in Chinese patients with left, right or bilateral brain damage. J Int Neuropsychol Soc. 2004 Jan;10(1):46-53. doi: 10.1017/S1355617704101069. |
| Background | Kong, A. P.-H., Hu, A. Z., Wong, C. C.-T., & Wong, C. W.-Y. (2025). Effects of modified word and sentence level gesture plus verbal treatment (GVT) in Cantonese speakers with aphasia. Aphasiology, 1-32. https://doi.org/10.1080/02687038.2025.2540297 |
| D009461 | Neurologic Manifestations |
| D009422 | Nervous System Diseases |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D007697 | Kinesics |
| D009633 | Nonverbal Communication |
| D003142 | Communication |
| D001519 | Behavior |