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This study plans to look at the benefits of banana leaves as a primary burn wound dressing. Study patients will be compared to historical patients
Historically, banana leaves have been used as a burn wound dressing in developing countries. Current literature on banana leaf dressings is limited to predominantly pediatric patients and surgical wounds (i.e. skin graft donor sites). The comparison dressing is often other non-standard burn dressings (e.g. boiled potato peel bandage) and these studies are almost exclusively performed in tropical locations where banana plants grow naturally (Africa and Asia). To date, no study on the effectiveness of banana leaf dressings has been done in the United States, nor has there been a focus on their effectiveness in second degree partial thickness burns. Our pilot study aims to establish the feasibility of using banana leaf dressings for second degree partial thickness burn wounds in adult patients, in a geographic location that does not support natural banana agriculture.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Banana leaf dressing | Experimental | Participants will be treated with banana leaf as a primary non-adherent dressing on their burn wounds |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Banana leaf dressing | Device | Sterilized banana leaf as a primary non-adherent burn dressing |
|
| Measure | Description | Time Frame |
|---|---|---|
| Pain scores, as measured using Number Pain Rating Scale | The Numeric Pain Rating Scale is a unidimensional subjective measure of pain intensity in adults, consisting of a scale from 0 to 10, where 0 represents "no pain" and 10 represents "worst pain imaginable" (or "worst possible pain"). | Before, during and after each wound care session during hospitalization, approximately 14 days |
| Measure | Description | Time Frame |
|---|---|---|
| Total use of opioids and benzodiazepines during wound care sessions | Total morphine-milligram equivalent (MME) and milligrams of benzodiazepines used during each wound care session | During hospitalization, approximately 14 days |
| Time to wound closure |
| Measure | Description | Time Frame |
|---|---|---|
| Patient recruitment rate | Average number of monthly patients recruited for the study | End of study (1 year) |
| Adherence to study intervention | Percentage of times patients enrolled in study received treatment with study intervention |
Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Cameron Gibson, MD | Contact | 720-848-3251 | cameron.2.gibson@cuanschutz.edu |
| Name | Affiliation | Role |
|---|---|---|
| Cameron Gibson, MD | University of Colorado, Denver | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Colorado Hospital | Aurora | Colorado | 80045 | United States |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 34765339 | Background | Chendake S, Kale T, Manavadaria Y, Motimath AS. Evaluation of Banana Leaves (Musa paradisiaca) as an Alternative Wound Dressing Material Compared to Conventional Petroleum Jelly Gauze Dressing in Contused, Lacerated and Sutured Wounds Over the Head, Neck and Face Region. Cureus. 2021 Oct 6;13(10):e18552. doi: 10.7759/cureus.18552. eCollection 2021 Oct. | |
| 23387359 |
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| ID | Term |
|---|---|
| D010146 | Pain |
| ID | Term |
|---|---|
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
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Clinical determination of burn wound closure to be made by study team
| During hospitalization or at follow-up in clinic, approximately within 1 month |
| Skin graft rate | Percentage of patients requiring skin grafting | During hospitalization, approximately 14 days |
| Burn wound infection rate | Percentage of patients who develop burn wound infection as defined by the American Burn Association | During hospitalization, approximately 14 days |
| Number of participants with at least one adverse event | Adverse events will only include those that are determined to be related to study device. | End of study (1 year) |
| End of study (1 year) |
| Adherence to pain score documentation | Percentage of properly documented pain scores during wound care sessions | End of study (1 year) |
| Guenova E, Hoetzenecker W, Kisuze G, Teske A, Heeg P, Voykov B, Hoetzenecker K, Schippert W, Moehrle M. Banana leaves as an alternative wound dressing. Dermatol Surg. 2013 Feb;39(2):290-7. doi: 10.1111/dsu.12067. Epub 2012 Dec 10. |
| 16766833 | Background | Srinivas CR, Sundaram VS, Raju BA, Prabhu SK, Thirumurthy M, Bhaskar AC. Achieving asepsis of banana leaves for the management of toxic epidermal necrolysis. Indian J Dermatol Venereol Leprol. 2006 May-Jun;72(3):201-2. doi: 10.4103/0378-6323.25779. |
| 12880731 | Background | Gore MA, Akolekar D. Evaluation of banana leaf dressing for partial thickness burn wounds. Burns. 2003 Aug;29(5):487-92. doi: 10.1016/s0305-4179(03)00050-0. |
| 12880730 | Background | Gore MA, Akolekar D. Banana leaf dressing for skin graft donor areas. Burns. 2003 Aug;29(5):483-6. doi: 10.1016/s0305-4179(03)00049-4. |
| 7971569 | Background | Dharnidharka VR, Kandoth PW. Use of banana leaves in Stevens-Johnson syndrome. Pediatr Dermatol. 1994 Sep;11(3):280-1. doi: 10.1111/j.1525-1470.1994.tb00606.x. No abstract available. |
| 25041616 | Background | Hop MJ, Polinder S, van der Vlies CH, Middelkoop E, van Baar ME. Costs of burn care: a systematic review. Wound Repair Regen. 2014 Jul-Aug;22(4):436-50. doi: 10.1111/wrr.12189. |