Safety and Tolerability Study of Human Neural Stem Cells for Huntington's Disease

Phase 1B/2A Study of the Safety and Tolerability of Human Neural Stem Cells for Huntington's Disease

The purpose of this research study is to determine whether an implantation of hNSC-01 is a safe and tolerable study intervention for Huntington's disease. This study is the first time that hNSC-01 is being tested in people.

Please note this may not be a complete list of eligibility criteria.

Inclusion Criteria:

• Have decision-making capacity and be able to provide written informed consent.
• Are between 18 to 65 years of age
• Have genetically confirmed diagnosis of Huntington's Disease
• Able to undergo MRI scans, tolerate neurosurgical procedure, blood draws and lumbar puncture.

Exclusion Criteria:

• Are pregnant
• Test positive for human immunodeficiency virus (HIV), hepatitis C or chronic hepatitis B at Screening
• Have an implanted deep brain stimulation device.