This prospective observational cohort study aims to investigate whether the weight-based equivalent (mg/kg) of a fixed 1 g dose of tranexamic acid administered during septorhinoplasty is associated with intraoperative remifentanil titration frequency and perceived anesthesiologist workload. Although tranexamic acid is routinely given as a fixed dose, its mg/kg equivalent varies according to patient weight and may influence hemodynamic management during controlled hypotension. The primary outcome is the total number of remifentanil infusion rate adjustments during surgery. Secondary outcomes include total remifentanil consumption and postoperative anesthesiologist workload assessed using the NASA Task Load Index (NASA-TLX).

Inclusion Criteria:

• Age ≥ 18 years
• Elective septorhinoplasty under general anesthesia
• Intraoperative administration of fixed 1 g intravenous tranexamic acid as part of routine practice
• Controlled hypotension strategy applied intraoperatively
• Surgery duration between 60-240 minutes
• Complete intraoperative hemodynamic and drug titration records available

Exclusion Criteria:

• Emergency surgery
• Additional major surgical procedure performed in the same session
• Known coagulation disorder
• Contraindication to tranexamic acid
• History of thromboembolic disease
• Chronic opioid use or opioid tolerance
• Chronic pain syndrome
• Regular use of sedatives, benzodiazepines, or CNS depressants
• Severe cardiac, renal, or hepatic failure
• Uncontrolled hypertension or significant arrhythmia
• Preoperative hemoglobin <10 g/dL
• Major intraoperative complication
• Incomplete or missing intraoperative data

Adult patients (18-70 years) undergoing elective septorhinoplasty under general anesthesia at a tertiary academic hospital. All patients receive a fixed 1 g intravenous dose of tranexamic acid as part of routine clinical practice, and intraoperative management includes a controlled hypotension strategy. Consecutive eligible patients with complete perioperative data are included in this prospective observational cohort.